Results 81 to 90 of about 740,226 (329)

Making Institutional Repositories Work

, 2015
Quickly following what many expected to be a wholesale revolution in library practices, institutional repositories encountered unforeseen problems and a surprising lack of impact. Clunky or cumbersome interfaces, lack of perceived value and use by scholars, fear of copyright infringement, and the like tended to dampen excitement and adoption.
Callicott, Burton B., Scherer, David, Wesolek, Andrew   +2 more
openaire   +5 more sources

Human iPSC‐Derived Mononuclear Phagocytes Improve Cognition and Neural Health across Multiple Mouse Models of Aging and Alzheimer's Disease

Advanced Science, EarlyView.
Short‐term intravenous treatments with iPSC‐derived mononuclear phagocytes (iMPs) improve cognitive decline and neural health in two mouse models of aging and in the 5xFAD mouse model of Alzheimer's disease. iMPs reduce levels of serum amyloid proteins that increase in aging and improve the health of hippocampal microglia and mossy cells.
V. Alexandra Moser, Luz Jovita Dimas‐Harms, Rachel M. Lipman, Jake Inzalaco, Shaughn Bell, Michelle Alcantara, Erikha Valenzuela, George Lawless, Simion Kreimer, Sarah J. Parker, Helen S. Goodridge, Clive N. Svendsen   +11 more
wiley   +1 more source

Designing the Cyberinfrastructure for Spatial Data Curation, Visualization, and Sharing

IASSIST Quarterly, 2017
Widely used across disciplines such as natural resources, social sciences, public health, humanities, and economics, spatial data is an important component in many studies and has promoted interdisciplinary research development.
Yue Li, Nicole Kong, Stanislav Pejša
doaj   +1 more source

The impact of institutional repositories: a systematic review

Journal of the Medical Library Association, 2020
Objective: Institutional repositories are platforms for presenting and publicizing scholarly output that might not be suitable to publish in a peer-reviewed journal or that must meet open access requirements. However, there are many challenges associated with their launch and up-keep. The objective of this systematic review was to define the impacts of
Michelle R. Demetres, Diana Delgado, Drew N. Wright   +2 more
openaire   +6 more sources

Integrative Omics Reveals Glutamine Catabolism‐Driven Apoptotic Suppression in Monocytes upon Mechanical Unloading

Advanced Science, EarlyView.
This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding, Fan Tong, Mingqiu Liu, Pin Yang, Jing Zeng, Yinghua Wei, Chunlin Li, Dong Li, Cheng Chang, Yangjun Zhang, Shaoqiong Yi, Fan Hu, Wenjie Shu, Lingqiang Zhang, Chun‐Ping Cui   +14 more
wiley   +1 more source

GLS1‐RNA Polymerase II Axis Mediates Glutamine‐Dependent Hepatoprotective Effects on Alcoholic Liver Disease in High‐Protein Diets

Advanced Science, EarlyView.
GLS1 interacts with RNA polymerase II subunits, ROLR2H and POLR2E, resulting in significant suppression of RNA polymerase II activity. Importantly, the investigation demonstrates that high‐protein diets, particularly glutamine, exert protective effects against alcoholic fatty liver through GLS1‐RNA polymerase II axis.
Wenbiao Wu, Haowen Jiang, Yichang Liu, Chang Peng, Hanlin Wang, Wenhua Yang, Zan Lyu, Yan Sun, Huan Ma, Hongyu Gu, Weijuan Kan, Liya Jing, Tiancheng Dong, Chunmei Xia, Saifei Lei, Rui Wu, Jinlong Li, Jia Li   +17 more
wiley   +1 more source

Creating an Institutional Repository [PDF]

, 2006
Institutional repository is a digital collection that capture, mantain, save, index, preserve and redistribute entire output of an institution in digital format. They adhere to open access modell and they are OAI – compliant. Building of insitutional repository is essential to the library whose mission is to provide access to wide range of information ...
Grozdanić, Marija, Macan, Bojan, Vodopijevec, Alen   +2 more
openaire   +1 more source

Workflow Development for an Institutional Repository in an Emerging Research Institution

Journal of Librarianship and Scholarly Communication, 2017
INTRODUCTION This paper describes the process librarians in the Albert B. Alkek Library at Texas State University undertook to increase the amount of faculty publications in their institutional repository, known as the Digital Collections. DESCRIPTION OF PROGRAM Digital Collections at Texas State University is built on a DSpace platform and serves as ...
Jeanne Hazzard, Stephanie Towery
openaire   +4 more sources

Nanographene Oxide Attenuates Acute GVHD by Modulating Macrophage Polarization in a Xenogeneic Mouse Model

Advanced Science, EarlyView.
Nanographene oxide (NGO) attenuates graft‐versus‐host disease (GVHD) severity by inhibiting STAT1‐mediated M1 macrophage polarization and suppressing T‐cell activation. NGO‐primed macrophages (NGO‐Mac) further enhance regulatory T‐cell induction via IL‐10. Both NGO and NGO‐Mac therapies mitigate inflammation and immune pathology, offering cell‐free and
Aaron Yu, Hyun Sung Park, Dong‐Hoon Chae, Jae Han Park, Jiyoung Heo, Keonwoo Cho, Jiho Kim, Hyewon Lee, Sueyeon Jee, Chanwoo Kim, Soon Won Choi, Jaechul Ryu, Eun‐Hye Hur, Yunsuk Choi, Eun‐Ji Choi, Mi‐Kyung Oh, Hwa‐Yong Lee, Je‐Hwan Lee, Kyung‐Rok Yu   +18 more
wiley   +1 more source

INSTITUTIONAL REPOSITORY: EMPLOYMENT IN EDUCATION

Інформаційні технології і засоби навчання, 2012
The article investigated the concept of «institutional repository» and determined the aspects of institutional repositories in higher education.
Vasyl P. Oleksyuk, Olesya R. Oleksyuk
doaj