Results 71 to 80 of about 10,736,528 (389)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

University governance and academic research : case studies of research units in Dutch and English universities [PDF]

, 2007
The central research question of our study addresses the effects of governing models on the research practices of basic research units in public universities in the fields of medieval history and biotechnology.
Leisyte, Liudvika
core   +1 more source

Doctorateness: where should we look for evidence? [PDF]

, 2017
This chapter considers the possibility of an “institutional theory of artistic research”. It proposes four distinct quadrants in which one might look for evidence for such a theory, which needs to have the capacity to accommodate the diverse positions on
Biggs, Michael
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Speaking for human being: institutional logics, dragons, and the supra-human

Revista Eletrônica de Ciência Administrativa
This essay engages with the mounting published criticism of neo-institutionalism, particularly the institutional logical approach. By addressing each of the main critiques formulated by the opponents of the theory – (1) institutional logical theory is ...
Roger Friedland, Diane-Laure Arjaliès
doaj   +1 more source

Internationalisation as Institutional Escape for Family Businesses in Conflict Zones: Evidence from Afghanistan

Entrepreneurial Business and Economics Review, 2019
Objective: The objective of this article is to investigate the use of internationalisation to “escape” the institutional voids present in conflict economic systems, through interviews with fifteen Afghan family business leaders who run ...
Muska Hanify, Omar Al Serhan, Sarath W.S.B. Dasanayaka, Kimberly Catherine Gleason   +3 more
doaj   +1 more source

Challenging Institutional Theory’s Critical Credentials

Organization Theory, 2019
Institutional theory’s claim to be critical rings hollow. Not only does the theory lack an emancipatory agenda but most institutional studies privilege agentic power over hegemonic.
K. Munir
semanticscholar   +1 more source

Atlantic trade and regional specialisation in nothern Spain 1550-1650: an integrated trade theory-institutional organisation approach [PDF]

, 2001
Based on an in-depth study of the northern Spanish economy in the sixteenth and seventeenth centuries, this paper argues that commercial expansion was a major source of the diverging performance of European regions.
Grafe, Regina
core   +2 more sources

Social and cultural origins of motivations to volunteer a comparison of university students in six countries [PDF]

, 2010
Although participation in volunteering and motivations to volunteer (MTV) have received substantial attention on the national level, particularly in the US, few studies have compared and explained these issues across cultural and political contexts. This
Anne Birgitta Pessi, Astin, A.W., Astin, A.W., Astin, A.W., Baum, F.C., Bozzo, S., Civicus, Crosby, O., Davis Smith, J., Devlin, R.A., Esping-Anderson, G., Femida Handy, Friedland, L., Gabard, D.L., Gillespie, D., Grönlund, H., Hall, M., Hall, M., Hall, M., Handy, F., Independent Sector, Jeffrey L. Brudney, Jones, F., Jones, F., Lesley Hustinx, Musick, M.A., Naoto Yamauchi, O’Brein, E.M., Ram A. Cnaan, Salamon, L.M., Salamon, L.M., Salamon, L.M., Salamon, L.M., Smith, E., Taniguchi, H., Tuan, Y., Volunteering in America, Wikipedia, Winniford, J.C., Wuthnow, R., Yamauchi, N., Yu-Ting C.M.   +41 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source