Results 61 to 70 of about 500,035 (241)
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Acta Universitatis Carolinae: Philologica, 2018 Book review: Svoboda, Tomáš and Łucja Biel and Krzysztof Łoboda (eds.) (2017) Quality Aspects in Institutional Translation.
Tereza Marková
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Translation commentary re-examined in the eyes of translator educators at British universities
JoSTrans: The Journal of Specialised Translation, 2018 Translation commentary is often used as an assessment method in translation degrees. In spite of this, relatively little attention has been paid to it empirically.
Claire Yi-yi Shih
doaj +1 more source
Disaster risk management or adaptation to climate change; How to deal with climate issue in Colombia? Analysis from agenda setting and traveling model perspectives of the elaboration of climate policies. [PDF]
, 2019 The main purpose of this work is to understand, in an actor oriented perspective, the context in which climate policy are formulated in a country, Colombia.
Howland, Fanny, Le Coq, Jean-François
core
Translation of a community palliative care intervention: experience from West Bengal, India [PDF]
, 2018 Background: The community form of palliative care first constructed in Kerala, India has gained recognition worldwide. Although it is the subject of important claims about its replicability elsewhere, little effort has gone into studying how this might ...
Clark, David +2 more
core +3 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Micro-strategies of Contextualization Cross-national Transfer of Socially Responsible Investment [PDF]
This paper examines how individuals select and mobilize local institutions when they transfer business practices across societies that are construed as dissimilar to one another.
Eva Boxenbaum, Jean-Pascal Gond
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source