Results 61 to 70 of about 872,727 (291)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
A Model of Creation? Scott, Sidney and Du Bartas [PDF]
, 2015 The copyright for this article belongs jointly to the Sidney Journal and to the author, and the Sidney Journal is willing to make the essay accessible via an institutional repository.William Scott’s translation from Guillaume de Saluste Du Bartas’ La ...
AUGER, PA
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Acta Universitatis Carolinae: Philologica, 2018 Book review: Svoboda, Tomáš and Łucja Biel and Krzysztof Łoboda (eds.) (2017) Quality Aspects in Institutional Translation.
Tereza Marková
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Translation commentary re-examined in the eyes of translator educators at British universities
JoSTrans: The Journal of Specialised Translation, 2018 Translation commentary is often used as an assessment method in translation degrees. In spite of this, relatively little attention has been paid to it empirically.
Claire Yi-yi Shih
doaj +1 more source
Micro-strategies of Contextualization Cross-national Transfer of Socially Responsible Investment [PDF]
This paper examines how individuals select and mobilize local institutions when they transfer business practices across societies that are construed as dissimilar to one another.
Eva Boxenbaum, Jean-Pascal Gond
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Belas Infiéis, 2016 This article examines the influence of the translation in the formation of cultural identities, following a text of Lawrence Venuti, in which he explains the process of translation and its effects, the representation of foreign cultures and the creation ...
Gisele Noce
doaj
Journal of Applied HermeneuticsIf we consider the claim made by Dr. Theodore George at the 15th annual Canadian Hermeneutic Institute Conference, that there are unique contexts that require an untethering of ourselves from our tradition to better put ourselves into question, or what ...
Katherine Stelfox
doaj +1 more source