Results 41 to 50 of about 128,473 (302)

Green criminology and the reconceptualization of school violence: Comparing green school violence and traditional forms of school violence for school children

, 2016
School crime and violence continue to be important topics of criminological inquiry. Forms of violence that have received much attention from criminologists include school gun violence, assaults, and bullying.
Stretesky, Paul, Barrett, Kimberly, Lynch, Michael   +2 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

School violence and the role of the school psychologist [PDF]

, 2002
Plan BThe purpose of this study was to determine school psychologists’ perceptions of the prevalence of school violence, to determine how safe school psychologists perceive their school(s) to be, to assess school psychologists’ reported experiences with ...
Arrowood, Renee Grace
core  

The criminalization of the rondero-peasant patrols in Peru as a case of institutional violence by the State

Sortuz
This research intends to analyse the causes of the lack of recognition, by the ordinary Peruvian justice system, of the rondero-peasant jurisdiction's decisions.
Julio Francisco Villarreal, Fanny Verónica Marrache Díaz, Gilmer Alarcón Requejo, Kori Lino Beltrán   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Obstetric Violence: Reproductive and Sexual Health Trajectories of Racialised Brazilian Women in Portugal

Social Sciences
Obstetric violence (OV) is a form of gender-based violence (GBV) that arises from the medicalisation of childbirth and the systematic devaluation of women’s bodies during pregnancy, childbirth, and the postpartum period.
Mariana Holanda Rusu, Conceição Nogueira, Joana Bessa Topa   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

“Living in the Darkness”: Technology-Facilitated Coercive Control, Disenfranchised Grief, and Institutional Betrayal

, 2023
This article draws on interviews with 20 Australian women subjected to technology-facilitated coercive control (TFCC), foregrounding their accounts of grief and institutional betrayal.
Dragiewicz, Molly, Woodlock, Delanie, Harris, Bridget, Salter, Michael   +3 more
core   +1 more source

The Risk Screener Violence (RS-V): retrospective prediction of violent and aggressive incidents within the prison setting

Frontiers in Psychology
IntroductionPhysical and verbal violence toward staff or other detained individuals is a reoccurring problem within correctional facilities. Screening for violence risk within the prison setting could provide a valuable first step in the prevention of ...
Marjam V. Smeekens, Marjam V. Smeekens, Michiel De Vries Robbé, Michiel De Vries Robbé, Michiel De Vries Robbé, Arne Popma, Maaike M. Kempes, Maaike M. Kempes   +7 more
doaj   +1 more source