Results 51 to 60 of about 4,667 (257)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Leder högre kvalitet på institutioner till mindre avskogning? : En empirisk studie baserad på Environmental Kuznets Curve [PDF]

, 2021
Skog är en viktig naturresurs för att sköta hållbar konsumtion, uppnå fattigdomslindring, stöda matanskaffning, bevara biodiversiteten och lindra klimatförändringen. En del länder har hög avskogningstakt medan andra läder har lägre.
Lindström, Alexander
core  

Demokratiskt kulturarv [Elektronisk resurs] : nationella institutioner, universella värden, lokala praktiker

, 2006
Frågan om ett demokratiskt kulturarv brukar knytas till 1974 års statliga kulturpolitik med sin ambition att sprida kultur till allt bredare grupper.
Aronsson, Peter,
core   +1 more source

Udkantsdanmark skal kortlægges

Geoforum Perspektiv, 2013
Overordnet set ved vi meget om, hvordan Udkantsdanmark udvikler sig. De unge rejser imod de større byer, ældrebyrden vokser, antallet af offentlige institutioner er lavt, og der er dårlige beskæftigelsesforhold.
Henrik Skov
doaj   +3 more sources

Human Potential in Motion: An Empowerment Approach to Productive Growth in Correctional Institutions

Jurnal Ilmiah Kebijakan Hukum
This study explores the empowerment strategies implemented at the Garut Class IIA Correctional Institution to activate inmates human potential, enhance productivity, and strengthen readiness for social reintegration. The research was conducted to address
Helena Gracelda Situmeang, Padmono Wibowo   +1 more
doaj   +1 more source

Uddannelse for bæredygtig udvikling på danske professionshøjskoler og universiteter

Tidsskrift for Professionsstudier, 2023
Artiklen undersøger, i hvilken grad bæredygtig udvikling optræder inden for strategiske satsninger blandt danske universiteter og professionshøjskoler (Lysgaard & Haase 2021). Dette sker på baggrund af en forståelse af, at danske institutioner rykker på
Jonas Andreasen Lysgaard, Sanne Haase
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Grundlæggende udfordringer med reglerne for undtagelsesfonde og selvejende institutioner

, 2020
Reglerne for henholdsvis selvejende institutioner, der i praksis snarere er (halv-)offentlige organer, samt egentlige fonde, som undtages fra fondslove som følge af, at de løser opgaver for det offentlige er komplekse, i visse henseende uhensigtsmæssige.
Feldthusen, Rasmus Kristian
core  

Lokala effekter av bistånd på tilltron till institutioner

, 2022
Medan vikten av att utveckla välfungerande statliga institutioner i utvecklingsländer är okontroversiell så är frågan om huruvida givare hjälper eller stjälper denna process omtvistad.
Isaksson, Ann-Sofie,, Durevall, Dick,
core