Results 111 to 120 of about 278,985 (267)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Linguistic Features of AI-Generated Scientific Manuscripts in Medical Fields: Writing Instruction for Biomedical Authors

open access: yesResearch in English Language Pedagogy
The advent of artificial intelligence (AI) has precipitated a paradigm shift in the methodologies employed for drafting scientific manuscripts, particularly within the biomedical field.
Nematullah Shomoossi   +3 more
doaj  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Metodologia wykładu patrologi-patrystyki w Polsce po „Instrukcji” z 1989 roku

open access: yesVox Patrum, 2008
In 1989, the Instruction on the Study of the Fathers of the Church in the Formation ofPriests was published. A document of the Congregation for Catholic Education, it provides a basic reference point for all lecturers on patrology.
Jan Słomka
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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