Results 101 to 110 of about 10,982,042 (291)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Usability in learning management systems: A mixed-method analysis

International Journal of Pioneering Technology and Engineering
Usability analysis in software has a critical role in creating useful products for users and obtaining the necessary feedback. Learning Management Systems (LMSs) are among the most frequently used software in distance education.
Pembe Pelin Koca, Hakan Özcan
doaj   +1 more source

How Project Management Skills Are Obtained by Instructional Designers

, 2021
Instructional designers need project management skills when managing instructional design projects (Liu et al., 2002). Based on a 2018 study, project management knowledge was found in over 40% of job postings and is recognized as a competency needed for ...
Jones, Tia Lee.
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Mechanism underlying revetment effects on the spatial distribution of nitrogen removal and N2O emissions in riparian zones at summer

Journal of Hydrology: Regional Studies
Study Region, Shanghai, China, Study FocusUrban riparian zones can mitigate or even control nitrogen pollution in rivers through nitrification and denitrification processes. However, these processes also produce N2O, a potent greenhouse gas.
Zihao Man, Changkun Xie, Ruiyuan Jiang, Jin Wang, Yanting Zhang, Shengquan Che   +5 more
doaj   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

An Instructional Design Primer [PDF]

, 2019
Much has been written in this forum about instructional design; however, for some followers, the primary concepts and principles of instructional design may yet be relatively new.
Wood, Rob
core   +1 more source

A systematic literature review and mapping of human-robot interaction in educational contexts

Humanities & Social Sciences Communications
This study presents a systematic mapping and literature review of human-robot interaction (HRI) in educational contexts, synthesizing empirical evidence to provide a comprehensive overview of the field’s current state.
Mehmet Tekerek, Zeynep Beyazaslan, Hamza Aydemir, Mehmet Gök   +3 more
doaj   +1 more source

Gender disparities in K-12 computer science education: Status, contributing factors, and instructional approaches

Computers and Education Open
This study conducts a systematic review of the literature to investigate gender disparities in K-12 computer science (CS) education. We selected articles published in peer-reviewed journals that focused on both cognitive and affective aspects of ...
Kyungbin Kwon, Sang Joon Lee, Keunjae Kim   +2 more
doaj   +1 more source