Results 121 to 130 of about 297,035 (311)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Instructional leadership among elementary school heads: Examining the relationships of demographic profiles, leadership practices and associated challenges

CTU Journal of Innovation and Sustainable Development
Effective management among teachers, staff, students, and parents requires strong instructional leadership of the school head. Thus, this study aims to investigate the instructional leadership practices and challenges of the school heads in elementary ...
Donnel Jay E. Tambis, Joan Sinagpulo, Jennifer Veruen, Medalla Palconit, Iris Gayrama   +4 more
doaj   +3 more sources

Instructional Practices Inventory: A Process for Profiling Student Engaged Learning for School Improvement [PDF]

, 2005
Further information may be found on the Middle Level Leadership Center web site at http://education.missouri.edu/orgs/mllc/4A_ipi_overview.phpA list of Middle Level Leadership Center's items within MOspace about Instructional Practices Inventory may be ...
Valentine, Jerry
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

A Phenomenological Narrative Study: Elementary Charter Principals\u27 Role as an Instructional Leader [PDF]

, 2018
The National Alliance for Public Charter Schools (NAPCS) (2013) defined charter schools on the company website as independent public schools allowed freedom to be more innovative, while being held accountable for improved student achievement (p.
Cetinkaya, Ahmet F.
core   +1 more source

The superintendent's maintenance and influence on classroom instructional capacity : a mixed method study [PDF]

The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf ...
Sayre, Chad William, 1974-
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

HAVA SINIF OKULLARI VE TEKNİK EĞİTİM MERKEZİ KOMUTANLIĞINDA GÖREV YAPAN OKUL YÖNETİCİLERİNİN ÖĞRETİMSEL LİDERLİK DAVRANIŞLARI

Havacılık ve Uzay Teknolojileri Dergisi, 2007
The general purpose of this research is to determine the instructional leadership behavior of school administrators working in the Air Services Schools and Technical Training Center Command.
M. Sinan Saygınar
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Does Principal Instructional Leadership Promote Teacher Instructional Engagement? Evidence from a Large-Scale Survey in China

Education Sciences
Teacher teaching engagement is a critical factor influencing teacher development and school quality. Based on survey data from 15,931 high school teachers and 1072 school principals from China, this study explores the impact of principals’ instructional ...
Xuelai Li, Yuki Gong, Junzuo Zhou, Ping Zhao   +3 more
doaj   +1 more source