Results 111 to 120 of about 1,114,734 (254)

INSTRUCTIONAL LEADERSHIP AND PROFESSIONAL LEARNING IN A RURAL NORTH CAROLINA SCHOOL DISTRICT

, 2014
This case study examined the instructional leadership of principals as co-participants in professional learning with teachers in a rural school district in eastern North Carolina.
Theus, Jeff
core   +1 more source

Examining the Self-Reported Instructional Leadership Practices of Science Heads of Departments in Lesotho Secondary Schools

Education Sciences
Instructional leadership is crucial for improving teaching quality and student academic performance, especially in secondary schools where Heads of Department (HoDs) play a vital role.
Lucia Nthooa Lisene, Loyiso Currell Jita, Thumah Mapulanga   +2 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Leadership Innovation and Inclusion in the City of Big Shoulders [PDF]

, 2019
Ever wonder how our emerging leaders frame and think about leadership? That insight could help us understand the future of leadership while revealing key priorities for leadership education, development, and research.
Cletzer, D. Adam, Alegbeleye, Ibukun Dami, Kaufman, Eric K.   +2 more
core  

Linking Instructional Leadership and Differentiated Instruction: Examining the Mediating Role of Teacher Agency

SAGE Open
This study explored how principal instructional leadership influences differentiated instruction by examining the mediating role of teacher agency. Utilizing a sample of 706 primary and secondary school teachers in Türkiye, this study employed structural
Muhammet Emin Türkoğlu, Ramazan Cansoy
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Towards the democratization of instructional leadership in South African schools: current trends and future possibilities. [PDF]

, 1995
Doctor EducationisThe Department of Education of the South Mrican Government of National Unity has accepted democratic governance as one of the principles of its education and training programme. At school level, especially at historically black schools,
Williams, Clarence Gordon
core  

Linear and nonlinear relationships between instructional leadership and teacher professional learning through teacher self-efficacy as a mediator: a partial least squares analysis

Humanities & Social Sciences Communications
Although the investigation of instructional leadership and teacher professional learning is well-documented in the literature, one overlooked question concerns the linear and nonlinear relationships between these two variables. This study aims to examine
Lei Mee Thien, Peng Liu
doaj   +1 more source