Results 91 to 100 of about 1,114,734 (254)

MODEL KEPEMIMPINAN INSTRUKSIONAL KEPALA SEKOLAH

open access: yesCakrawala Pendidikan: Jurnal Ilmiah Pendidikan, 2015
Abstrak: Penelitian ini bertujuan untuk menemukan model kepemimpinan instruksional kepala sekolah. Penelitian ini menggunakan pendekatan kualitatif dengan jenis multikasus. Instrumen penelitan adalah peneliti sendiri.
Husaini Usman
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Leadership Activities and Behaviours that Enable Classroom Teachers [PDF]

open access: yes, 2010
Leadership has a well researched and significant influence on the quality of school organisation and student learning. Much of the research has centred on educational leadership theory and the opinions and perspectives of serving principals.
Al-Abbas, Abdullah Adlan
core  

Carol Ann Tomlinson, “The Differentiated Classroom: Responding to the Needs of All Learners.” Alexandria, VA: ASCD, 2014.

open access: yesResearch and Education
Carol Ann Tomlinson’s The Differentiated Classroom is a foundational work in the field of inclusive pedagogy and instructional design. It advocates for responsive teaching that accommodates students’ diverse needs, interests, readiness levels, and ...
Stephen Kwame Ameko   +2 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Perceptions and practices of principals: examining instructional leadership for curriculum reform

open access: yesFrontiers in Education
A theoretical and empirical grounded explanation is constructed on how primary school principals perceive and enact instructional leadership during curriculum reform.
Moeketsi David Ralebese   +2 more
doaj   +1 more source

Towards a leadership programme for primary school principals as instructional leaders

open access: yesSouth African Journal of Childhood Education, 2016
This study set out to explore primary school principals’ instructional leadership. The study addressed a key issue in the school improvement literature, pertaining to the curriculum leadership of principals.
Parvathy Naidoo, Nadine Petersen
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

How principals' instructional leadership impacts schools' middle leadership

open access: yes
Instructional leadership is a school leadership approach that prioritizes enhancing the quality of teaching and learning. This study explores how the principal's instructional leadership influences the school's middle leadership.
Shaked, Haim
core   +1 more source

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