Results 21 to 30 of about 3,475,630 (306)

Serious Games in Higher Distance Education

open access: yesCanadian Journal of Learning and Technology, 2021
Games have been socially entrenched throughout history as a form of entertainment. Current rapidly changing technological advances have permitted an increasingly prominent means of utilizing these sources of entertainment in an instructional capacity for
Ann Celestini
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Intellectual Pyramiding as Instructional Strategy for Teaching Campus Journalism Skills

open access: yesJPAIR, 2009
Campus publication is like a heterogeneous classroom where students bring multiple perspectives to the informal classroom for budding journalists: diverse backgrounds, learning styles, experiences, and aspirations thus, teacher advisers/moderators ...
Juancho M. Babista
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Code-switching as an Instructional Strategy in a Multilingual Classroom Setting: Examining Its Effects on the instruction of the Sesotho Home Language [PDF]

open access: yesJournal of Education and Learning Technology
Code-switching remains an enduring and widespread feature of linguistic contact in many South African communities. This study investigated the pedagogical and sociolinguistic implications of code-switching in multilingual South African classrooms by ...
Soyiso Khetoa
doaj   +1 more source

Development of instructional strategy of computer application software for group instruction

open access: yes, 2009
This study was designed to develop practical and effective teaching strategies of computer application software for group instruction at Tamkang University. The assumption was that practical strategies for learning computer application software that were
Lee, Shih-chung
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Teacher perceptions of Literacy Pedagogical practices on learner transition: The case of Grade 3- 4 EFAL in Oliver Reginald Tambo Inland District, Eastern Cape, South Africa [PDF]

open access: yesJournal of Education and Learning Technology
This paper utilizes a qualitative research approach to explore teachers’ perceptions of literacy pedagogical practices and their impact on learners transitioning from Grade 3 to Grade 4 in English First Additional Language (EFAL). Rooted in sociocultural
Mkululi Lele
doaj   +1 more source

Engaging learners in complex, authentic contexts: Instructional design for the web [PDF]

open access: yes, 2000
The old adage, 'We teach as we have been taught' places a great deal of responsibility on the current generation of online teachers, to teach in a manner that is worth replicating.
Oliver, R., Herrington, J., Stoney, S.
core  

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