Results 21 to 30 of about 11,087 (125)

Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Stable lentiviral vector producer cell lines represent a promising platform for scalable and cost‐efficient vector manufacturing, yet their productivity is often limited by intrinsic host‐cell constraints. In this study, we aimed to identify cellular factors restricting LVV production in stable doxycycline‐inducible GPRTG producer cell lines ...
Jona Röscheise, Lena‐Marie Eberle, Holger Laux, Kerstin Otte   +3 more
wiley   +1 more source

When Aviation CSR Efforts Are Not Enough: How Do We Inspire Airline Passengers to Offset Their Travel Footprints?

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Voluntary carbon offsetting programs (VCOPs) are available for airline passengers who want to take action and offset their scope 3 emissions. Yet, their uptake is very limited. In this study, we propose an integrated theoretical model involving the norm activation theory and protection motivation theory to understand airline passengers ...
Eric Tchouamou Njoya, Michael Adu Kwarteng, Alex Ntsiful, Abderrahmane Sadou, Marina Efthymiou   +4 more
wiley   +1 more source

Differential sensitivity to SHH signaling and neural crest‐mediated Gas1 expression regulate jaw size during development and evolution

Developmental Dynamics, EarlyView.
Abstract Background Developmental control of jaw size is crucial to prevent birth defects and facilitate evolutionary adaptation. We have shown that jaw size is established by neural crest mesenchyme (NCM), which are progenitor cells that migrate into the mandibular primordia and produce the jaws.
Zuzana Vavrušová, Daniel B. Chu, An Nguyen, Yeniko Ta, Jennifer L. Fish, Richard A. Schneider   +5 more
wiley   +1 more source

Antimicrobial Sensitivity Profile and Resistance Gene Research in Escherichia coli Isolated From Water and Fish From Lagoa da Conceição, Florianópolis, SC, Brazil

Food Safety and Health, EarlyView.
This paper highlights a concerning scenario of environmental contamination by multidrug‐resistant bacteria, underscoring the need for integrated surveillance and control strategies to address antimicrobial resistance in aquatic environments within the context of One Health.
Francisco Lucas de Amorim Nascimento, Luan Amaral Alexandre, Cynthia Farias Manassi, Alice Cristina da Silva, Luísa Aimée Schmitt Lobe, Gustavo Rocha, Mateus Rocha Ribas, Victor Wolleck, Gabriele Caroline Gottschalk de Abreu, Alessandra Valéria Vortmann, Sheila Mello da Silveira, Rodrigo Barcellos Hoff, Jussara Kasuko Palmeiro, Silvani Verruck   +13 more
wiley   +1 more source

Effects of Social Capital on Career Development Competency Among Young People With Chronic Disabling Health Conditions: Mediating Role of Chronic Illness Self‐Management

Journal of Employment Counseling, EarlyView.
ABSTRACT This study explores how social capital and chronic illness self‐management influence career development competency among young people with chronic disabling health conditions (YPCDHC) in Hong Kong. Using data from 485 participants aged 15–29, path analysis showed that school/workplace social capital had the strongest positive effects on career
Steven Sek‐yum Ngai, Chau‐kiu Cheung, Yuen‐hang Ng, Pamela Pui‐yu Leung, Mike Kwun‐ting Cheung, Hanlei Du, Haoyi Guo, Yongjia He, Hiu‐lam Ngai, Laing‐ming Wong, Qiushi Zhou   +10 more
wiley   +1 more source

Proteomic Signatures of Ectopic Fat Distribution: Tissue‐Specific Drivers and Clinical Implications

Med Research, EarlyView.
Integration of plasma proteomics and multi‐organ MRI in 666 UK Biobank participants, combined with a knockoff‐based causal inference and machine learning framework, reveals organ‐specific drivers of ectopic fat: PLA2G1B (pancreas), ERBB2/IGFBP2 (liver), CA14 (muscle), and NCAM2/TNFRSF10B (pericardium). These drivers engage distinct pathways (e.g., PI3K‐
Bing Zhang, Fen Yang, Xingji Lian, Jie He, Shuijin Huang, Mingjuan Fan, Yin Liang, Jiaqiang Huang, LongYan Yin, Hong Wang   +9 more
wiley   +1 more source

Hands‐on and Minds‐on? Findings on the Instructional Support of Preschool Teachers to Foster Children's Understanding of Scientific Practices

Science Education, EarlyView.
ABSTRACT To participate effectively in modern society, it is essential to have both knowledge of scientific concepts and an understanding of scientific practices. Children develop initial knowledge and skills to engage in scientific practices, such as identifying patterns, long before entering school.
Ada Cecil Haen, Henrik Saalbach, Ilonca Hardy, Miriam Leuchter, Mirjam Steffensky   +4 more
wiley   +1 more source

2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions

Small, EarlyView.
Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom, Jae Hun Ahn, Jung Yung Kim, Kyo Chul Lee, Yong Jin Lee, Sanoj Rejinold N, Jin‐Ho Choy   +6 more
wiley   +1 more source

Accelerating Mission Engineering: Evidence of a Stratified Landscape and a Path Toward Unified Practice

Systems Engineering, EarlyView.
ABSTRACT Mission Engineering is maturing as a Systems Engineering discipline, yet adoption of its common frameworks remains stratified. This study examines whether selective adoption is observable across ME scholarship and develops a framework to address identified barriers.
James Moreland, Nathaniel Ambler, Casey LaMar, Maegen Nix, Craig Sawyer   +4 more
wiley   +1 more source

Assessment of Oxidative Stress, Vitellogenin, and Human Health Risks Derived From Nile Tilapia Exposed to Metals and Metalloids in Southeastern Brazil

Environmental Toxicology, EarlyView.
ABSTRACT Urban coastal lagoons are highly vulnerable ecosystems increasingly affected by metal contamination, as well as multiple anthropogenic stressors. This study evaluated ecotoxicological and human health risks associated with chronic metal exposure in Nile tilapia (Oreochromis niloticus) from an anthropogenically impacted lagoon in southeastern ...
Julia Araújo Alves, Priscila M. O. Muniz Cunha, Shênia Patrícia Corrêa Novo, Lorena Oliveira Souza Soares, Tatiana Dillenburg Saint‐Pierre, Fábio Veríssimo Correia, André Luís de Sá Salomão, Rachel Ann Hauser‐Davis, Enrico Mendes Saggioro   +8 more
wiley   +1 more source