Results 31 to 40 of about 734,192 (264)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Cultural adaptation to Brazil of the questionnaire Costs of caring for children with cancer. [PDF]

, 2014
Objectiveto present the cultural adaptation of the questionnaire Costs of caring for children with cancer, offering a valid and reliable tool to assess the economic repercussions of childhood cancer for Brazilian families.Methodit is a methodological ...
dos Santos, Bruna Domingos, dos Santos, Claudia Benedita, Jacob, Eufemia, Marques, Amanda Rossi, Nascimento, Lucila Castanheira, Pan, Raquel   +5 more
core   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Implementation of ROSA radio occultation data handling into EUMETSAT and GRAS SAF processing [PDF]

, 2012
Within this contribution, outcomes from a GRAS - SAF Visiting Scientist activity focused on the analysis of ROSA data quality for their use in operational weather forecasting will be described and main results will be shown.
Andrea, Y., De Cosmo, V., Foresi, A., Lauritsen, K., Marquardt, C., Notarpietro, Riccardo, Von Engeln, A., Zin, A.   +7 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

PhoSim-NIRCam: Photon-by-photon image simulations of the James Webb Space Telescope's Near-Infrared Camera

, 2019
Recent instrumentation projects have allocated resources to develop codes for simulating astronomical images. Novel physics-based models are essential for understanding telescope, instrument, and environmental systematics in observations.
Burke, Colin J., Egami, Eiichi, Leisenring, Jarron M., Peterson, John R., Rieke, Marcia J., Sembroski, Glenn H.   +5 more
core   +1 more source

Robustness of geography as an instrument to assess impact of climate change on agriculture [PDF]

, 2018
The empirical literature on climate change and agriculture does not adequately address the issue of potential endogeneity between climatic variables and agriculture which makes their estimates unreliable.
Haider, Azad, Husnain, Muhammad Iftikh Ul, Subramanian, Arjunan   +2 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Adaptation and validation of the instrument positions on the nursing process [PDF]

Revista Latino-Americana de Enfermagem, 2013
OBJECTIVE: estimate the psychometric properties in the adaptation of the instrument Positions on Nursing Diagnosis to assess nursing staff members' attitudes towards the nursing process. METHOD: methodological study with a non-probabilistic sample of 973 nursing assistants and 632 baccalaureate nurses from 35 hospitals and outpatient clinics affiliated
Guedes, Erika de Souza, Sousa, Regina Marcia Cardoso de, Turrini, Ruth Natalia Teresa, Baltar, Valéria Troncoso, Cruz, Diná de Almeida Lopes Monteiro da   +4 more
openaire   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source