Results 101 to 110 of about 418,975 (381)

Validation of the Everyday Technology Use Questionnaire in a Japanese context

Hong Kong Journal of Occupational Therapy, 2015
Background/Objective: The Everyday Technology Use Questionnaire (ETUQ), which evaluates the perceived relevance of and the perceived ability in everyday technology (ET) use, has demonstrated acceptable psychometric properties in Swedish studies of older ...
Camilla Malinowsky, Anders Kottorp, Rumi Tanemura, Eric Asaba, Toru Nagao, Kazue Noda, Jiro Sagara, Peter Bontje, Lena Rosenberg, Louise Nygård   +9 more
doaj   +1 more source

The Parkinson's Disease Activities of Daily Living, Interference, and Dependence Instrument [PDF]

Movement Disorders Clinical Practice, 2019
ABSTRACTBackgroundIndividuals with Parkinson's disease often experience periods of off time when their motor symptoms are poorly controlled, significantly impacting their lives.ObjectivesTo identify the consequences of motor fluctuations on day‐to‐day activities and areas of unmet treatment priority among individuals with moderate to advanced Parkinson'
Emuella Flood, David Gray, Daniela E. Myers, Jacob Devine, Linda S. Deal   +4 more
openaire   +3 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Correlation Between Instrumental Hand Function and Activities of Daily Living in Rheumatoid Arthritis [PDF]

, 2009
Objective: To find the correlation of instrumental handfunction (grip strength, muscle power and range ofmotion) and Activities of Daily Living (ADL) inrheumatoid arthritis patients.Methods: 50 patients of either sex were included in thestudy.
Borah D, Gupta AK, Kumar A, Pandey RM, Singh U, Wadhwa S, Yadav SL   +6 more
core  

Impairment of Instrumental Activities of Daily Living in Patients with Mild Cognitive Impairment [PDF]

, 2009
ObjectiveaaThis study was conducted to examine the following: whether patients with mild cognitive impairment (MCI) show impairments in instrumental activities of daily living (IADL) as compared to controls; to identify the functional sub-domains of ...
Artero, Christensen, Doh Kwan Kim, Farias, Griffith, Hyeran Kim, Hyo Shin Kang, Inn Sook Ahn, Jae Won Chung, Ji-Hae Kim, Kang, Ku, Ku, Morris, Nygård, Okonkwo, Perneczky, Perneczky, Petersen, Pérès, Ritchie, Seonwoo Kim, Tabert, Winblad   +23 more
core   +3 more sources

The relationship between basic, instrumental, and advanced activities of daily living and executive functioning in geriatric patients with neurocognitive disorders

International Journal of Geriatric Psychiatry, 2019
Although many studies explored the relationship between executive functions (EF) and activities of daily living (ADLs) in cognitive disorders, previous studies used measurements without well‐defined levels of ADLs.
E. Cornelis, E. Gorus, Nele Van Schelvergem, Patricia de Vriendt   +3 more
semanticscholar   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Changes in Physical Function, Mental Status, and Independence in Daily Activities of Older People in Wirobrajan, Yogyakarta [PDF]

, 2016
BACKGROUND: The increasing population of older people in Indonesia induces research to understand their characteristics and changes over time. These data are needed to develop appropriate health programs for older people.
Ferni, F. (Ferni), Harjosuwano, S. S. (Slamet), Meilina, M. (Meilina), Widagdo, M. M. (Maria)   +3 more
core   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source