Results 61 to 70 of about 393,540 (338)

Effect of Cognitive Training on Daily Function in Older People without Major Neurocognitive Disorder: A Systematic Review

Geriatrics, 2019
There is increasing interest in the effect of non-pharmacological treatments on preserving cognition and function in older adults without major neurocognitive disorder (dementia).
Brian J.Y. Fan, Roger Y.M. Wong
doaj   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Effects of anxiety on neurocognitive performance in HIV positive adults [PDF]

, 2014
Objective: To examine the effects of anxiety on neuropsychological performance among HIV positive adults in Lusaka, Zambia.Design: A cross-sectional study with a sample of 263 participants of who 107 (40.7%) were males and 156 (59.3%) were females ...
Heaton, RK, Hestad, K, Menon, AJ, Ncheka, JM, Paul, R   +4 more
core   +2 more sources

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Residential greenness, activities of daily living, and instrumental activities of daily living [PDF]

Environmental Epidemiology, 2019
Background:We aimed to explore whether higher levels of residential greenness were related to lower odds of disabilities in activities of daily living (ADL) and instrumental activities of daily living (IADL).Methods:We included older adults 65 years of age or older from the Chinese Longitudinal Healthy Longevity Survey.
Zhu, Anna, Yan, Lijing, Wu, Chih-Da, James, Peter, Zeng, Yi, Ji, John   +5 more
openaire   +4 more sources

Burden of cirrhosis on older Americans and their families: Analysis of the health and retirement study [PDF]

, 2012
Prevalence of cirrhosis among older adults is expected to increase; therefore, we studied the health status, functional disability, and need for supportive care in a large national sample of individuals with cirrhosis. A prospective cohort of individuals
Adams, Anderson, Arno, Bajaj, Berman, Bialek, Chien, Coleman, Coolman, Dangleben, Davis, Demaerschalk, Dennis, Dominguez, Evans, Gleckman, Goldacre, Grant, Gupta, Gure, Hepburn, Hickenbottom, Hooley, Iwashyna, Kalra, Langa, McAdams, McCullagh, Nguyen, Piette, Rosland, Ruhl, Saunders, Shim, Smith, van den Berg, Vijan, Volk   +37 more
core   +1 more source

The Relationship of Basic and Instrumental Activities of Daily Living With the Risk of Developing Pressure Ulcer

Journal of Client-centered Nursing Care, 2018
Background: The basic and instrumental activities of daily living are prerequisites for living with a good quality of life. On the contrary, lack of movement and physical inactivity are considered as the main cause of pressure injuries. Accordingly, this
Sahar Mohammadi, Forough Rafii, Tahmine Salehi, Hamid Haghani   +3 more
doaj  

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Publicly funded home care for older people in Ireland: Determinants of utilisation and policy implications [PDF]

, 2012
Background: The majority of older people are independent and self caring. When long-term care is required this is provided across a range of community and residential settings including the older person’s own home.
Foley, MJ, Hickey, M, McClade, C, Molloy, DW, O Caoimh, R, O Regan, N, Timmons, S, Trawley, Steven   +7 more
core   +1 more source