Results 101 to 110 of about 886,705 (287)

The fibre broadband housing premium across three US States

open access: yesRegional Studies, Regional Science
This paper meshes 1.7 million housing transactions across three US states (Iowa, Minnesota and Texas) between 2015 and 2021 with data on broadband infrastructure to evaluate the impact of fibre broadband availability on home prices.
Brian Whitacre
doaj   +1 more source

The Instrumental Weighted Variables. Part II. Square root of n-consistency [PDF]

open access: yes
The definition of Instrumental Weighted Variables (IWV) (which is a robust version of the classical Instrumental Variables) and conditions for the weak consistency as given in the Part I of this paper are recalled.
Jan Ámos Víšek
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Association between Gut Microbiota and Biological Aging: A Two-Sample Mendelian Randomization Study

open access: yesMicroorganisms
Recent observational studies revealed an association between gut microbiota and aging, but whether gut microbiota are causally associated with the aging process remains unknown.
Chenglin Ye   +5 more
doaj   +1 more source

Predicting the Direction of Causal Effect Based on an Instrumental Variable Analysis: A Cautionary Tale

open access: yesJournal of Causal Inference, 2016
An instrumental variable can be used to test the causal null hypothesis that an exposure has no causal effect on the outcome, by assessing the association between the instrumental variable and the outcome.
Burgess Stephen, Small Dylan S.
doaj   +1 more source

Diagnosis Measurement Error and Corrected Instrumental Variables [PDF]

open access: yes
Health diagnosis indicators used as explanatory variables in econometric models often suffer from substantial measurement error. This measurement error can lead to seriously biased inferences about the effects of health conditions on the outcome measure ...
Chen, Donna   +3 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Non-Asymptotic Inference in Instrumental Variables Estimation

open access: yes, 2017
This paper presents a simple method for carrying out inference in a wide variety of possibly nonlinear IV models under weak assumptions. The method is non-asymptotic in the sense that it provides a finite sample bound on the difference between the true ...
Horowitz, Joel L.
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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