Results 41 to 50 of about 23,904 (284)

QUANTUM THEOLOGY BEYOND COPENHAGEN: TAKING FUNDAMENTALISM LITERALLY

open access: yesZygon, 2023
Theological engagement with quantum physics has, to this day, been dominated by the Copenhagen interpretation. However, philosophers and physicists working in the “quantum foundations” field have largely abandoned the Copenhagen view on account of what ...
doaj   +2 more sources

Should Scientists Embrace Scientific Realism or Antirealism? [PDF]

open access: yes, 2019
If scientists embrace scientific realism, they can use a scientific theory to explain and predict observables and unobservables. If, however, they embrace scientific antirealism, they cannot use a scientific theory to explain observables and ...
Park, Seungbae
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Organizational downsizing and the instrumental worker: Is there a connection? [PDF]

open access: yes, 2006
A national population sample of 424 employees was used to explore the proposition that the widespread use of organizational downsizing by management has led employees to adopt a more instrumental orientation to the employment relationship.
Macky, Keith
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Functional Fit and the Instrumental Character of Knowledge: Rethinking the Theory of Knowledge with Radical Constructivism [PDF]

open access: yesJournal of Philosophical Investigations
Radical constructivism (RC), introduced by Ernst von Glasersfeld, is an instrumentalist theory of knowledge that challenges the notion of knowledge as a picture or representation of a real, external world. Instead, RC, by integrating ideas from different
Meysam Khanjanian Mian-Poshte
doaj   +1 more source

An Instrumentalist Account of How to Weigh Epistemic and Practical Reasons for Belief [PDF]

open access: yes, 2019
When one has both epistemic and practical reasons for or against some belief, how do these reasons combine into an all-things-considered reason for or against that belief?
Skipper, Mattias   +1 more
core  

Countering student 'instrumentalism' through creative mediation [PDF]

open access: yes, 2003
One of the most significant features of the educational reforms introduced since 1989 has been the emphasis on raising achievement levels. One of the dangers of this emphasis is that teachers and learners become instrumental in their approach to teaching
Jeffrey, Bob
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Proiectul lui C. Rădulescu-Motru de fundamentare a psihologiei ca știință a naturii

open access: yesStudii de Istorie a Filosofiei Româneşti, 2023
In his early writings, Rădulescu-Motru acknowledged as a valuable gain the fact that psychology had emancipated itself from the tutelage of metaphysics. However, he believed that this progress could not lead to a scientific psychology unless its outcomes
Mona Mamulea
doaj   +1 more source

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