Results 101 to 110 of about 75,607 (300)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Development of a miniature mass analyzer and associated instrumentation for improved capabilities in the analysis of low energy plasmas from a rocket or satellite platform [PDF]

The University of Texas at Dallas (UTD) Center for Space Sciences (CSS) has designed, developed, and fabricated three miniature mass spectrometers and their associated instrumentation in fulfillment of a NASA contract. The ion mass spectrometer analyzers
Hoffman, John H.
core   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

A Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller

International Journal of Adaptive Control and Signal Processing, EarlyView.
Block Diagram of the Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller. ABSTRACT This article introduces a discrete‐time robust adaptive one‐sample‐ahead preview super‐twisting sliding mode controller. A stability analysis of the controller by Lyapunov criteria is developed to demonstrate its robustness in handling both ...
Guilherme Vieira Hollweg, Paulo Jefferson Dias de Oliveira Evald, Shivam Chaturvedi, Hilton Abilio Gründling, Rodrigo Varella Tambara, Wencong Su   +5 more
wiley   +1 more source

Innovating Aircraft Repair Processes: The Role of Digitalization in Sustainability

Advanced Engineering Materials, EarlyView.
This research explores how digitalization—by storing detailed non‐destructive testing data in structured DICONDE databases and creating a standard data model of the component—innovates aviation maintenance and repair processes. Coupled with a developed state‐based simulation model, it enables data‐driven, sustainable repair strategies that reduce waste,
Johanna Aigner, Geo Jacob, Florian Raddatz, Gerko Wende   +3 more
wiley   +1 more source

Development of a prototype for submarine communications in shallow waters [PDF]

, 2016
The Telecommunications Marine Laboratory (TML) of the University of Cádiz takes part in a research project to study the intertidal sediments of the Bay of Cádiz. The collection of samples from the seabed and the transmission of data to the surface are
Bohórquez Ferrando, Julio, Corzo Rodríguez, Alfonso, Figueroa Recio, Manuel, Gómez Castillo, Leopoldo, Mariscal Rico, Luis A., Papaspyrou, Sokratis, Rychkov, Eugene   +6 more
core  

Duplex Stainless Steel Laser‐Surface Textured: Stability in Brine Solution

Advanced Engineering Materials, EarlyView.
Controlled laser‐surface treatment (LST) of duplex DSS2205 steel is performed to increase its stability in brine solution under cyclic electrochemical assays. The superior protection with respect to flat and smooth panels is attributed to the presence of FeCr2O4 as the main protective oxide layer in the LST surface, after corrosion tests. The stability
Mohammad Rezayat, Hamidreza Enshaei, Elaine Armelin, José I. Iribarren, Antonio Mateo, Miguel Morales   +5 more
wiley   +1 more source

The Implementation of a High-Performance Glucose Biosensor Based on Differential EGFET and Chopper Amplifier

IEEE Journal of the Electron Devices Society
In this paper, a new architecture for glucose biosensors is proposed, which adopts a Chopper amplifier instead of a conventional instrumentation amplifier (INA) and differential extended gate field effect transistor (EGFET) as the input stage.
Po-Yu Kuo, Chi-Han Liao, Jung-Chuan Chou, Chih-Hsien Lai, Yu-Hsun Nien, Po-Hui Yang, Ming-Tai Hsu, Cheng-Chun Lien, Wei-Shun Chen, Jyun-Ming Huang, Yu-Wei Chen   +10 more
doaj   +1 more source

Multimodal Mechanical Testing of Additively Manufactured Ti6Al4V Lattice Structures: Compression, Bending, and Fatigue

Advanced Engineering Materials, EarlyView.
In this experimental study, the mechanical properties of additively manufactured Ti‐6Al‐4V lattice structures of different geometries are characterized using compression, four point bending and fatigue testing. While TPMS designs show superior fatigue resistance, SplitP and Honeycomb lattice structures combine high stiffness and strength. The resulting
Klaus Burkart, Jonas Schmidt, Anastasiya Toenjes, Johanna Eisenträger   +3 more
wiley   +1 more source