Results 81 to 90 of about 579,501 (376)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A Modified Bipolar Translinear Cell with Improved Linear Range and Its Applications [PDF]

, 2012
This paper presents a technique to extend the linear input voltage range of a sinh mixed translinear cell proposed by Fabre [1]. This technique extends the linear operation range of the circuit by inserting common-anode-connected pairs into the mixed ...
Kiranon, W., Merz, N., Narksarp, W., Pawarangkoon, P., Wongtachathum, C.   +4 more
core   +1 more source

Measurement of Flow Characteristics in a Bubbling Fluidized Bed Using Electrostatic Sensor Arrays [PDF]

, 2016
Fluidized beds are widely applied in a range of industrial processes. In order to maintain the efficient operation of a fluidized bed, the flow parameters in the bed should be monitored continuously. In this paper, electrostatic sensor arrays are used to
Wang, Jingdai, Yan, Yong, Yang, Yongrong, Zhang, Wenbiao   +3 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

A virtual lock-in amplifier,spectrum analyzer,impedance meter and semiconductor analyzer implemented on an SR7265 hardware target

Journal of Measurement Science and Instrumentation, 2018
Lock-in amplifiers are used to detect and measure very small alternating current（AC）signals down to the range of nVs.Accurate measurements can be made even when the small signals are buried by noise thousands of times larger.With the digital signal ...
BAI Jiang-hua, Freeouf L John, Andres La Rosa   +2 more
doaj  

An Investigative Redesign of the ECG and EMG Signal Conditioning Circuits for Two-fault Tolerance and Circuit Improvement [PDF]

, 1991
An investigation was undertaken to make the elctrocardiography (ECG) and the electromyography (EMG) signal conditioning circuits two-fault tolerant and to update the circuitry.
Obrien, Edward M.
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Clinical value of bioelectrical properties of cancerous tissue in advanced epithelial ovarian cancer patients [PDF]

, 2018
Currently, there are no valid pre-operatively established biomarkers or algorithms that can accurately predict surgical and clinical outcome for patients with advanced epithelial ovarian cancer (EOC).
Boutelle, Martyn G., Cunnea, Paula, Curry, Ed, Domenici, Lavinia, Drakakis, Emmanuel M., Fotopoulou, Christina, Gabra, Hani, Gorgy, Tommy, Gowers, Sally A. N., Lawton, Phillip, Leng Leong, Chi, Lu, Haonan, Morera, Cristina, Nixon, Katherine, Paterson, Andrew, Petkos, Konstantinos, Sorbi, Flavia, Wu, Wen   +17 more
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Toward Long Range Detection of Elephants Using Seismic Signals: A Geophone-Sensor Interface for Embedded Systems

IEEE Access
The long-distance detection of the presence of elephants is pivotal to addressing the human-elephant conflict. IoT-based solutions utilizing seismic signals originating from the movement of elephants are a novel approach to solving this problem.
Jaliya L. Wijayaraja, Janaka L. Wijekoon, Malitha Wijesundara, L. J. Mendis Wickramasinghe   +3 more
doaj   +1 more source