Results 71 to 80 of about 75,607 (300)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Simple system for locating ground loops [PDF]

, 2007
A simple low-cost system for rapid identification of the cables causing ground loops in complex instrumentation configurations is described. The system consists of an exciter module that generates a 100 kHz ground loop current and a detector module that ...
Bellan, P. M.
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

INTERFACE ADAPTATION DESIGN FOR EXTRACELLULAR RECORDINGS FROM EXCITABLE TISSUE

Journal of Engineering Science (Chişinău)
For a clear and almost exhaustive perspective on the physiology of living organisms, it is important to use the best method to sample the signal and to process it correctly, without affecting the content of information.
OANCEA, Constantin-Daniel
doaj   +1 more source

Universal conveyor instrumentation amplifier

Electronics Letters, 1989
A new instrumentation amplifier based on the use of current conveyors is proposed that exhibits a high common-mode rejection ratio without the need for any resistor matching. High differential gains and wide bandwidths are available simultaneously without compromise for both voltage and current inputs.
openaire   +1 more source

An Investigative Redesign of the ECG and EMG Signal Conditioning Circuits for Two-fault Tolerance and Circuit Improvement [PDF]

, 1991
An investigation was undertaken to make the elctrocardiography (ECG) and the electromyography (EMG) signal conditioning circuits two-fault tolerant and to update the circuitry.
Obrien, Edward M.
core   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Implementation of Time and Frequency Response Analysis for Web-Based Laboratories [PDF]

Journal of Systemics, Cybernetics and Informatics, 2011
The University of Dar Es Salaam has developed the web-based laboratory for Time and Frequency Response Analysis. The purpose of this web-based laboratory is the utilization of real data from real experiments, in terms of instrumentation and experimental ...
Teyana Sapula, Damian Haule
doaj  

Real-Time Telemetry System for Amperometric and Potentiometric Electrochemical Sensors

Sensors, 2011
A real-time telemetry system, which consists of readout circuits, an analog-to-digital converter (ADC), a microcontroller unit (MCU), a graphical user interface (GUI), and a radio frequency (RF) transceiver, is proposed for amperometric and ...
Ching-Hsing Luo, Cheng-Feng Wu, Wen-Fong Wang, Tse-Chuan Chou, Chih-Hsien Hu, Kuo-Chuan Ho, Chia-Yu Lin, Hong-Yi Huang, Shu-Chun Chen, Wei-Song Wang   +9 more
doaj   +1 more source