Results 61 to 70 of about 513,786 (307)

Frequency Based Phacoemulsification, and Calibrated Phacoemulsification Probe Tip: A Journey of Innovations

Delhi Journal of Ophthalmology, 2023
In today’s era, when instruments and machines decide what kind of ophthalmic advances would come up in the future, doctors have silently given the baton to engineers and industry.
Taru Dewan
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

CUSTOMER SATISFACTION REGARDING BANK’S DISTRIBUTION CHANNELS – THE ATM NETWORK [PDF]

Annals of the University of Oradea: Economic Science, 2010
In addition to traditional distribution methods (network of territorial units), to better meet market requirements in terms of speed and efficiency of services, banks have developed interactive electronic and computerized systems for clients: banking ...
Zaharie Monica Maria, Maniu Andreea Ioana, Radomir Lacramioara, Scridon Mircea Andrei   +3 more
doaj  

Evaluation and Optimization of Task-oriented Measurement Uncertainty for Coordinate Measuring Machines Based on Geometrical Product Specifications

Applied Sciences, 2018
Measuring instruments are intended to be intelligent, precise, multi-functional and developing multidirectionally, scientific, and reasonable; the reliable evaluation of measurement uncertainty of precision instruments is also becoming more and more ...
Yinbao Cheng, Zhongyu Wang, Xiaohuai Chen, Yaru Li, Hongyang Li, Hongli Li, Hanbin Wang   +6 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

MarsBots: Robotic Learning Module [PDF]

, 2006
This learning module offers hands-on, minds-on activities investigating the Martian environment and robotic technologies of space exploration. The learning module contains 16 national standards-based lessons designed to progress logically from learning ...

core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Agricultural Equipment and Machinery Usage Projection: Elazığ Province, Türkiye

Türkiye Tarımsal Araştırmalar Dergisi
With the rapidly developing technology in the word, increasing production in agriculture and saving labor and time increases the importance of agricultural mechanization.
Orhan KARA, Emine ARSLAN
doaj   +1 more source

A Conceptual Framework for Motion Based Music Applications [PDF]

, 2015
Imaginary projections are the core of the framework for motion based music applications presented in this paper. Their design depends on the space covered by the motion tracking device, but also on the musical feature involved in the application.
CANAZZA TARGON, Sergio, Mandanici, Marcella, Roda', Antonio   +2 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source