Results 151 to 160 of about 16,072,973 (241)

Renal insulin-like growth factor binding-protein 7 is a critical promoter of progressive diabetic kidney disease. [PDF]

Nat Commun
Yu JT, Hu XW, Wang JN, Yang Q, Li XY, Shan RR, Pu T, Hou R, Shen XY, Wang YQ, Zhang F, Yu XW, Wang J, Li FH, Wen JG, Fan Y, Jin J, Jiang YY, Meng XM.   +18 more
europepmc   +1 more source

Matrix Stiffness Orchestrates Mesenchymal Stem Cell Lineage Commitment Toward Osteogenesis and Adipogenesis Through the PIEZO1/SP1/STC2 Axis

Advanced Science, EarlyView.
Matrix stiffness directs mesenchymal stem cell lineage commitment through PIEZO1‐dependent activation of the SP1/STC2 pathway. Stiff matrices favor osteogenesis and suppress adipogenesis, whereas the loss of PIEZO1 function impairs early bone formation. STC2 retains lineage‐regulatory activity even when PIEZO1 is inactive.
Shuo Zhang, Siteng Li, Wenzhong Chen, Qingcheng Song, Haiyue Zhao, Peng Wang, Yiran Zhang, Wenquan Liang, Shaowei Zheng, Juan Wang, Wei Chen, Yanbin Zhu, Yingze Zhang   +12 more
wiley   +1 more source

Redox Biology and Insulin-like Growth Factor-Binding Protein-6: A Potential Relationship. [PDF]

Biology (Basel)
Coda ARD, Liso A, Bellanti F.
europepmc   +1 more source

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

Advanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia, Xu Gao, Laimin Zhu, Haixia Song, Jing Wu, Shang Chen, Sheng Gao, Lu Zhang, Chunyang Meng   +8 more
wiley   +1 more source

The expression of insulin-like growth factor binding proteins is tissue specific during human fetal life and early infancy [PDF]

, 1992
Eisenmenger, Wolfgang, Kiess, W., Kolb, H. J., Funk, B., Kessler, U., Hansmann, A.   +5 more
core   +1 more source

Causal associations between insulin-like growth factor binding protein-1 to -7 and osteoporosis: A two-sample Mendelian randomization study. [PDF]

Medicine (Baltimore)
Du P, Li T, Fan N, Wang B, Wang T, Zang L.   +5 more
europepmc   +1 more source

Insulin-like growth factor 1 and insulin-like growth factor binding protein 2 serum levels as potential biomarkers in differential diagnosis between chronic pancreatitis and pancreatic adenocarcinoma in reference to pancreatic diabetes

Gastroenterology Review, 2020
Barbara Włodarczyk, Anna Borkowska, Przemysław Włodarczyk, Ewa Małecka-Panas, Anita Gąsiorowska   +4 more
doaj   +1 more source

Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure

Advanced Science, EarlyView.
Mesenchymal stromal cell (MSC)‐based cell‐drug conjugates are constructed by anchoring rosiglitazone‐loaded nanoparticles onto the MSC surface. Sustained rosiglitazone release enhances MSC proliferation and paracrine activity while promoting anti‐inflammatory macrophage polarization.
Tenghui Ye, Jiamin Wu, Zixin Wu, Xi Liu, Jiajia Luo, Leyi Yang, Peng Shi   +6 more
wiley   +1 more source

ERRATUM: Effect of insulin-like growth factor binding protein-1 on integrin signalling and the induction of apoptosis in human breast cancer cells. [PDF]

J Mol Endocrinol
Perks CM, Newcomb PV, Norman MR, Holly JM.   +3 more
europepmc   +1 more source

Insulin-like growth factor binding protein-1 and insulin in polycystic ovary syndrome: a systematic review and meta-analysis. [PDF]

Front Endocrinol (Lausanne), 2023
Jin Y, Sun F, Yang A, Yu X, Li Y, Liang S, Jing X, Wang K, Zhang L, Xiao S, Zhang W, Wang X, Zhao G, Gao B.   +13 more
europepmc   +1 more source