Results 211 to 220 of about 16,072,973 (241)

ELF5‐Mediated Enhancer–Promoter Interaction Regulates LALBA Expression in Ovine Mammary Gland

Advanced Science, EarlyView.
In the study, we systematically investigate the epigenetic mechanisms underlying lactation traits in sheep by integrating transcriptomic, chromatin accessibility, histone modification, and functional analyses. We identify a super‐enhancer at the LALBA locus and demonstrate that enhancer E4 functions as its core regulatory element.
Xinmiao Wu, Jiqing Wang, Zhiyun Hao, Mingna Li, Huimin Zhen, Yuan Liu, Guoyong Zhao, Chunyan Ren, Xuelan Zhou, Haixiong Hu, Mingjie Li, Nan Shi   +11 more
wiley   +1 more source

Association of baseline and longitudinal changes in insulin-like growth factor-binding protein-7 with the risk of incident heart failure: Data from the PREVEND study. [PDF]

Eur J Heart Fail
Abou Kamar S, Bracun V, El-Qendouci M, Bomer N, Bakker SJL, Gansevoort RT, Boersma E, Kardys I, de Boer RA, Suthahar N.   +9 more
europepmc   +1 more source

Establishment and characterization of mouse lymph node fibrosis models

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu, Xu Guan, Jian Ma, Xin Zhang, Yihang Shi, Jinzhu Zhang, Leiqiong Gao, Wei Chen, Xishan Wang   +8 more
wiley   +1 more source

Clinicopathological correlation of insulin-like growth factor binding protein 3 and their death receptor in patients with gastric cancer. [PDF]

Res Pharm Sci
Ansari A, Gheysarzadeh A, Sharifi A, Mofid MR.   +3 more
europepmc   +1 more source

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

Correlation of tri-ponderal mass index with insulin-like growth factor-I and insulin-like growth factor binding protein-3 in children and adolescents. [PDF]

Ann Pediatr Endocrinol Metab
Choi IH, Kim SY, Kim M.
europepmc   +1 more source

Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients

Annals of Neurology, EarlyView.
Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer, Seth Frietze, Serena W.R. Lewis, Emily C. Artman, Christina Coughlan, Safa I. Vaseemuddin, Arianna Gentile Polese, Maria A. Nagel, Stephen K. Tyring, Fyona Okundia, Anthony J. Saviola, Gary C. Curhan, Sharon G. Curhan, Diego Restrepo, Andrew N. Bubak   +14 more
wiley   +1 more source

Expression and pathogenesis of insulin-like growth factor-1 and insulin-like growth factor binding protein 3 in a mouse model of ulcerative colitis. [PDF]

Heliyon
Wang W, Sun X, Wang A, Lu Y, Han Y, Zhao J, Liu F, Tian Z.   +7 more
europepmc   +1 more source

Insulin-Like Growth Factor Binding Protein 2 Predicts Right Ventricular Reverse Remodeling and Improvement of Concomitant Tricuspid Regurgitation After Transcatheter Edge-to-Edge Mitral Valve Repair. [PDF]

Clin Cardiol
Gröger M, Felbel D, Paukovitsch M, Schneider LM, Markovic S, Rottbauer W, Keßler M.   +6 more
europepmc   +1 more source

Serum Insulin-like Growth Factor-Binding Protein-2 as a Prognostic Factor for COVID-19 Severity. [PDF]

Biomedicines
Mester P, Räth U, Schmid S, Amend P, Keller D, Krautbauer S, Bondarenko S, Müller M, Buechler C, Pavel V.   +9 more
europepmc   +1 more source