Results 241 to 250 of about 31,548,076 (283)

Insulin‐like growth factor‐binding protein 1 and insulin‐like growth factor‐binding protein 3 in pre‐eclampsia

BJOG: An International Journal of Obstetrics & Gynaecology, 1996
Objective To investigate circulating levels of insulin‐like growth factor‐binding protein 1 (IGFBP‐1) and IGFBP‐3 in the mother and the fetus in pregnancies complicated by pre‐eclampsia, and the relationship between serum levels of IGFBPs and fetal birthweight.Design A prospective study over an 18 month period.Setting A tertiary care ...
H S, Wang, J D, Lee, B J, Cheng, Y K, Soong   +3 more
openaire   +2 more sources

Bovine lactoferrin binds to insulin-like growth factor-binding protein-3

Domestic Animal Endocrinology, 2003
Insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) has been shown to have IGF independent actions that appear to be mediated by specific IGFBP-3 binding proteins located on cell membranes. We show here using Western ligand blotting, a number of mammary membrane proteins that bind 125I-labeled rhIGFBP-3.
C R, Baumrucker, C A, Gibson, F L, Schanbacher   +2 more
openaire   +2 more sources

Differential dissociation kinetics explain the binding preference of insulin-like growth factor binding protein-6 for insulin-like growth factor-II over insulin-like growth factor-I [PDF]

FEBS Letters, 1999
Insulin-like growth factor binding protein-6 binds insulin-like growth factor-II with a marked preferential affinity over insulin-like growth factor-I. The kinetic basis of this binding preference was studied using surface plasmon resonance.
Mark Hogarth, Leon Bach
exaly   +2 more sources

Insulin-like growth factor-1 and insulin-like growth factor-binding protein-3 in women with premenstrual syndrome

Fertility and Sterility, 1998
To determine whether women with premenstrual syndrome (PMS) have aberrations of the GH axis as has been demonstrated in individuals with depression.Prospective trial.Department of Obstetrics and Gynecology, University of California, Los Angeles.After prospective screening, 32 healthy women with PMS and 32 asymptomatic controls completed the study ...
A J, Rapkin, M, Cedars, M, Morgan, L, Goldman   +3 more
openaire   +2 more sources

Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3

Journal of the American Academy of Dermatology, 2000
A recent report suggested that men with vertex balding have higher levels of plasma insulin-like growth factor 1 (IGF-1). The association of its major carrier protein, insulin-like growth factor binding protein 3 (IGFBP-3), with male pattern hair loss has not been examined.We evaluated the relations of plasma concentrations of IGF-1 and IGFBP-3 with ...
E A, Platz, M N, Pollak, W C, Willett, E, Giovannucci   +3 more
openaire   +2 more sources

Insulin-like growth factor binding-protein-3 (IGFBP–3)

Best Practice & Research Clinical Endocrinology & Metabolism, 2015
The IGF system comprises two IGFs (IGF-1, IGF-2), two IGF-receptors (IGF-R1, IGF-R2), and six IGF binding proteins (IGFBPs) with a high affinity for IGFs. The IGFBPs, of which IGFBP-3 is the most abundant in postnatal blood, link with IGFs and prevent them from being degraded; they also facilitate IGF transport through body compartments.
openaire   +2 more sources

Insulin-like growth factors, insulin-like growth factor-binding proteins, insulin-like growth factor-binding protein-3 protease, and growth hormone-binding protein in lipodystrophic Human Immunodeficiency Virus-infected patients

Metabolism, 2004
Human immunodeficiency virus (HIV)-lipodystrophy is associated with impaired growth hormone (GH) secretion. It remains to be elucidated whether insulin-like growth factors (IGFs), IGF-binding proteins (IGFBPs), IGFBP-3 protease, and GH-binding protein (GHBP) are abnormal in HIV-lipodystrophy.
Steen B, Haugaard, Ove, Andersen, Birgitte R, Hansen, Hans, Orskov, Ulrik B, Andersen, Sten, Madsbad, Johan, Iversen, Allan, Flyvbjerg   +7 more
openaire   +2 more sources

Cellular Actions of Insulin-Like Growth Factor Binding Protein-3

1994
Insulin-like growth factor I (IGF-I) plays a major role in regulating growth of cells in vivo and in vitro (1). IGF-I initiates metabolic and mitogenic processes in a wide variety of cell types by binding to specific type I IGF receptors in the plasma membrane (2).
C A, Conover, J T, Clarkson, S K, Durham, L K, Bale   +3 more
openaire   +2 more sources

Regulation and Actions of Insulin-Like Growth Factor Binding Protein-3

1991
Binding proteins for the insulin-like growth factors (IGFs), first described 15 years ago, are now recognized as playing important roles as carriers of IGFs in the circulation, and modulators of IGF actions on target cells 1. Three distinct structural classes of IGF binding protein (IGFBP) have been identified on the basis of cDNA cloning 2–6, and at ...
R C, Baxter, J L, Martin
openaire   +2 more sources

Serum Levels of Insulin-like Growth Factor-I and Insulin-like Growth Factor Binding Protein-3 in Obese Children

Journal of Pediatric Endocrinology and Metabolism, 1997
Growth hormone (GH) and insulin-like growth factor-I (IGF-I) metabolism may be disturbed in obese children. We investigated serum GH, IGF-I, IGF-binding protein-3 (IGFBP-3) levels in 42 obese and 40 non-obese healthy children aged 6-14 years. GH stimulation tests with L-dopa and insulin were performed.
Bideci, AYSUN, Elbeg, S, Hasanoglu, A, Cinaz, P   +3 more
openaire   +3 more sources