Results 261 to 270 of about 405,429 (298)

Insulin-like growth factor-1 and insulin-like growth factor-binding protein-3 in women with premenstrual syndrome

Fertility and Sterility, 1998
To determine whether women with premenstrual syndrome (PMS) have aberrations of the GH axis as has been demonstrated in individuals with depression.Prospective trial.Department of Obstetrics and Gynecology, University of California, Los Angeles.After prospective screening, 32 healthy women with PMS and 32 asymptomatic controls completed the study ...
A J, Rapkin, M, Cedars, M, Morgan, L, Goldman   +3 more
openaire   +2 more sources

Insulin-like growth factor-I/insulin-like growth factor binding protein-3 alters lymphocyte responsiveness following severe burn

Journal of Surgical Research, 2004
Following severe burn, patients are immunocompromised, making them at increased risk for infection. Exogenous growth hormone has been shown to partially restore immune function. Herein, we investigated Th1/Th2 cytokine profiles and cellular proliferation in isolated mononuclear cells after treatment with exogenous insulin-like growth factor-I (IGF-I ...
Steven E, Wolf, Kenneth J, Woodside, Roque J, Ramirez, Makiko, Kobayashi, Fujio, Suzuki, David N, Herndon   +5 more
openaire   +2 more sources

Serum Levels of Insulin-like Growth Factor-I and Insulin-like Growth Factor Binding Protein-3 in Obese Children

Journal of Pediatric Endocrinology and Metabolism, 1997
Growth hormone (GH) and insulin-like growth factor-I (IGF-I) metabolism may be disturbed in obese children. We investigated serum GH, IGF-I, IGF-binding protein-3 (IGFBP-3) levels in 42 obese and 40 non-obese healthy children aged 6-14 years. GH stimulation tests with L-dopa and insulin were performed.
Bideci, AYSUN, Elbeg, S, Hasanoglu, A, Cinaz, P   +3 more
openaire   +3 more sources

Serum insulin-like growth factor-I and insulin-like growth factor binding protein-3 in premature rupture of membranes

Acta Obstetricia et Gynecologica Scandinavica, 2002
Background.  The aim of the study was to evaluate whether the circulating levels of insulin‐like growth factor‐I (IGF‐I) and its major circulating binding protein, IGFBP‐3, are affected in premature rupture of membranes (PROM) and preterm delivery.Methods.
Mikko, Loukovaara, Riitta, Koistinen, Tarja, Kalme, Tapio, Kurki, Pekka, Leinonen, Markku, Seppälä   +5 more
openaire   +2 more sources

Somatomedin-1 binding protein-3

BioDrugs, 2003
Somatomedin-1 binding protein-3 [insulin-like growth factor-1 binding protein-3, SomatoKine] is a recombinant complex of insulin-like growth factor-1 (rhIGF-1) and binding protein-3 (IGFBP-3), which is the major circulating somatomedin (insulin-like growth factor) binding protein; binding protein-3 regulates the delivery of somatomedin-1 to target ...
openaire   +2 more sources

Insulin-like growth factor binding protein-3 in normal pubertal girls

Acta Endocrinologica, 1992
IGFBP-3 concentrations rise in the second decade of life. To test the hypothesis that the stage of pubertal development, independent of chronological age, was associated with these increases we measured serum IGFBP-3 concentrations by radioimmunoassay in 324 sixth and seventh grade girls (12.3±0.7 years) at the beginning of a multisite school-based ...
D M, Wilson, M A, Stene, J D, Killen, L D, Hammer, I F, Litt, C, Hayward, C B, Taylor   +6 more
openaire   +2 more sources

Insulin-like growth factor–binding protein-3 and breast cancer survival

International Journal of Cancer, 1998
Insulin-like growth factors (IGFs) are potent mitogens involved in the regulation of cell proliferation and apoptosis. The action of IGFs is mediated through a specific cell membrane receptor (IGF-IR), and the interactions between IGFs and this receptor are regulated by IGF-binding proteins (IGFBPs).
H, Yu, M A, Levesque, M J, Khosravi, A, Papanastasiou-Diamandi, G M, Clark, E P, Diamandis   +5 more
openaire   +2 more sources

Insulin-like Growth Factor Binding Protein 3 in Inflammatory Bowel Disease

Digestive Diseases and Sciences, 2005
Epithelial cell growth regulation has been reported to be altered in inflammatory bowel disease (IBD) patients. The cell growth regulatory factor, insulin-like growth factor binding protein 3 (IGFBP-3), may be partly responsible for this phenomenon. So far, IGFBP-3 levels have been assessed as values of total protein, which is a sum of bioactive intact
Kirman, Irena, Whelan, Richard Larry, Jain, Suvinit, Nielsen, Sara Elsøe, Seidelin, Jakob Benedict, Nielsen, Ole Haagen   +5 more
openaire   +2 more sources

Insulin-Like Growth Factor Binding Protein-3 Inhibits Colitis-Induced Carcinogenesis

Diseases of the Colon & Rectum, 2007
Chronic inflammation in the setting of inflammatory bowel disease is thought to result in altered epithelial cell growth regulation and ultimately carcinogenesis. This loss in cell growth regulation may be partially caused by a decrease in circulating intact insulin-like growth factor binding protein-3 (IFGB-3) as a result of chronic inflammation. This
A, Belizon, E, Balik, I, Kirman, H, Remotti, N, Ciau, S, Jain, R L, Whelan   +6 more
openaire   +2 more sources

PROTEINS IN TISSUE EXTRACTS WHICH BIND INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-3 (IGFBP-3)

Journal of Endocrinology, 1995
ABSTRACT Membrane associated IGFBP-3 is now known to play a role in the modulation of IGF at the cellular level, but mechanisms involved in cell membrane binding are far from certain. In this study we report the identification and initial structural characterisation of proteins in a range of sheep and rat tissues which specifically bind ...
S, Hodgkinson, P, Fowke, N, al Somai, M, McQuoid   +3 more
openaire   +2 more sources