Results 101 to 110 of about 33,649,900 (305)

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali   +4 more
wiley   +1 more source

Relationship between geometric mean (95% CI) of insulin-like growth factor component levels with dietary intake.

open access: yes, 2014
Insulin-like Growth Factor, IGF; Insulin-like Growth Factor Binding Protein, IGFBP; P value is based on T test.Relationship between geometric mean (95% CI) of insulin-like growth factor component levels with dietary intake.
Jennifer S. Smith (283828)   +9 more
core   +1 more source

Insulin-Like Growth Factor I Prevents Cellular Aging via Activation of Mitophagy

open access: yesJournal of Aging Research, 2020
Mitochondrial dysfunction is a hallmark of cellular aging. Mitophagy is a critical mitochondrial quality control mechanism that removes dysfunctional mitochondria and contributes to cell survival. Insulin-like growth factor 1 (IGF-1) promotes survival of
Xuwei Hou   +4 more
doaj   +1 more source

Insulin-like growth factor I in essential hypertension

open access: yesKidney International, 1999
mmol/liter; serum cholesterol, 5.95 mmol/liter; serum triglycerides, 1.40 mmol/liter; serum potassium, 4 mmol/liter; serum creatinine, 95 mmol/liter (1.1 mg/dl); creatinine clearance, 112 ml/min/1.73 m body surface; and 24-hour urine albumin excretion, 245 mg. Urinalysis revealed no other abnormalities.
Principal discussant, , Díez, Javier
openaire   +3 more sources

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks   +8 more
wiley   +1 more source

Age-related loss of skeletal muscle function; impairment of gene expression. [PDF]

open access: yes, 2004
Mechano Growth Factor (MGF) is derived from the insulin-like growth factor (IGF-I) but its sequence differs from the systemic IGF-I produced by the liver. MGF is expressed by mechanically overloaded muscle and is involved in tissue repair and adaptation.
Goldspink, G
core  

Supplementary Material from A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling in vitro and inhibits insulin-like growth factor-I receptor–dependent tumor growth in vivo

open access: yes, 2007
Supplementary Material from A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling in vitro and inhibits insulin-like growth factor-I receptor–dependent tumor growth in
Gilda Mak (15042473)   +13 more
core   +1 more source

DDX3 Regulates Reproduction in Locusta migratoria Potentially via Insulin/Insulin-like Growth Factor Signaling

open access: yesInsects
Locusta migratoria (Orthoptera: Acrididae) is a major agricultural pest, characterized by its strong reproductive capacity and rapid reproduction rate.
Yi Jin   +8 more
doaj   +1 more source

Patients improve, patterns persist: longitudinal stability of RA joint involvement patterns

open access: yesArthritis Care &Research, Accepted Article.
Objective Rheumatoid arthritis is a heterogeneous disease. Data‐driven approaches, from synovial histology to joint involvement patterns (JIPs), have sought to define clinically meaningful subgroups. Whether these subgroups represent stable phenotypes or transient disease states remains unclear.
Tjardo Maarseveen   +24 more
wiley   +1 more source

2D Skeletal Muscle Thin Film Actuators Enhance Efficiency of Biohybrid Robots

open access: yesAdvanced Functional Materials, EarlyView.
2D skeletal muscle thin film actuators generate millinewton‐scale forces and millimeter‐scale strokes while remaining functional for over 30 days. Their force density is 20‐fold higher than 3D skeletal muscle actuators, enabling multi‐fin robots with tunable speed and multidirectional steering.
Maheera Bawa   +5 more
wiley   +1 more source

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