Results 101 to 110 of about 530,055 (311)

Effects of insulin-like growth factor-I on the maturation of metabolism in neonatal rat cardiomyocytes [PDF]

, 2018
Myocardial metabolism shifts during the perinatal period from predominant utilization of glucose towards oxidation of fatty acids. Expression of enzymes of the fatty acid oxidation (FAO) pathway is under the control of the nuclear receptor/transcription ...
Lerch, René, Montessuit, Christophe, Palma, Tatiana, Pellieux, Corinne, Viglino, Christelle   +4 more
core  

Increased expression of leptin and the leptin receptor as a marker of breast cancer progression: possible role of obesity-related stimuli [PDF]

, 2006
PURPOSE: Recent in vitro studies suggested that the autocrine leptin loop might contribute to breast cancer development by enhancing cell growth and survival.
CASCIO, Sandra, GAROFALO C, GOLASZEWSKA J, KANCZUGA KODA L, KODA M, RUSSO, Antonio, SULKOWSKA M, SULKOWSKI S, SURMACZ E.   +8 more
core   +1 more source

Transfer Printing and Reconfiguration of Soft Electronics Using Digital Microfluidics and Laser Machining

Advanced Functional Materials, EarlyView.
This paper presents a digital microfluidics‐based technique for transferring and reconfiguring soft nanomembranes. Laser‐machined nanothin membranes are picked up, transported, and aligned via tailored surface tension and the actuation of water droplets, enabling the development of flexible electronics, the integration of functional materials on 3D ...
Quang Anh Nguyen, Chi Cong Nguyen, Tran Bach Dang, Phuoc Thien Phan, Jordan Thorpe, Michael Listyawan, Nhat Minh Doan, Sinuo Zhao, Hongru Chen, Trung Thien Hoang, Mingsheng Xu, Jisheng Han, Thanh Nho Do, Adam Hill, Timothée Mouterde, Hoang‐Phuong Phan   +15 more
wiley   +1 more source

Type I insulin-like growth factor as a liver reserve assessment tool in hepatocellular carcinoma

Journal of Hepatocellular Carcinoma, 2015
Reham Abdel-Wahab,1,2 Samir Shehata,2 Manal M Hassan,1 Mouhammed A Habra,3 Ghazaleh Eskandari,4 Peggy T Tinkey,5 Jennifer Mitchell,5 Ju-Seog Lee,6 Hesham M Amin,4,7 Ahmed O Kaseb11Department of Gastrointestinal Medical Oncology, The University of Texas ...
Abdel-Wahab R, Shehata S, Hassan MM, Habra MA, Eskandari G, Tinkey PT, Mitchell J, Lee JS, Amin HM, Kaseb AO   +9 more
doaj  

Somatotropic Axis and Obesity: Is There Any Role for the Mediterranean Diet? [PDF]

, 2019
Obesity is associated with reduced spontaneous and stimulated growth hormone (GH) secretion and basal insulin-like growth factor I (IGF-1) levels-which in turn is associated with increased prevalence of cardiovascular risk factors.
Barrea, L., Colao, A., Di Somma, C., Laudisio, D., Muscogiuri, G., Pugliese, G., Salzano, C., Savastano, S.   +7 more
core   +1 more source

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

Advanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang, Myungji Kim, Hwanyong Choi, Jinseon Park, Minji Kim, Donghwan Kim, Bo Ram Lee, Jinah Jang   +7 more
wiley   +1 more source

Insulin-Like Growth Factor I Prevents Cellular Aging via Activation of Mitophagy

Journal of Aging Research, 2020
Mitochondrial dysfunction is a hallmark of cellular aging. Mitophagy is a critical mitochondrial quality control mechanism that removes dysfunctional mitochondria and contributes to cell survival. Insulin-like growth factor 1 (IGF-1) promotes survival of
Xuwei Hou, Zhaohui Li, Yusuke Higashi, Patrice Delafontaine, Sergiy Sukhanov   +4 more
doaj   +1 more source

An association between lifespan and variation in insulin-like growth factor I receptor in sheep [PDF]

, 2011
Longevity in livestock is a valuable trait. When productive animals live longer, fewer replacement animals need to be raised. However, selection for longevity is not commonly the focus of breeding programs as direct selection for long-lived breeding ...
Byun, Seung O., Forrest, Rachel, Frampton, Christopher M., Hickford, Jonathan G. H., Zhou, Huitong   +4 more
core   +1 more source

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

Advanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang, Tadahiro Yamashita, Ryo Sudo   +2 more
wiley   +1 more source

The matricellular functions of small leucine-rich proteoglycans (SLRPs) [PDF]

, 2009
The small leucine-rich proteoglycans (SLRPs) are biologically active components of the extracellular matrix (ECM), consisting of a protein core with leucine rich-repeat (LRR) motifs covalently linked to glycosaminoglycan (GAG) side chains.
Rosetta Merline, Roland M. Schaefer, Liliana Schaefer   +2 more
core   +1 more source