Results 171 to 180 of about 2,026,798 (359)

Improving global access to medicines for non-communicable diseases

The Lancet Global Health, 2014
David Beran, Christophe Perrin, Nils Billo, John S Yudkin   +3 more
doaj   +1 more source

Haemostasiologic effects of various glucose-lowering medications in type 2 diabetes mellitus

Кардиоваскулярная терапия и профилактика, 2010
Aim. To evaluate the effects of insulin and other glucose-lowering medications on platelet function and coagulation haemostasis in patients with Type 2 diabetes mellitus (DM-2). Material and methods.
G. G. Petrik, S. A. Pavlishchuk
doaj  

Microalbuminuria and Insulin Resistance

, 2009
The glomerular barrier is highly selective and only minute amounts reaches the urine. Normally, the daily loss of albumin in urine is less than 30 mg and microalbuminuria denotes losses between 30-300 mg per day.
Haraldsson, Börje,
core  

Lean, Non-Autoimmune Young-Onset Diabetes in Bangladesh: A Metabolically Obese Phenotype With Disproportionate Insulin Secretory Defect. [PDF]

Endocrinol Diabetes Metab
Hasan M, Sultana N, Shil KK, Salam SBA, Ashraf K, Bhuiyan AAN, Al Masud MO, Ratul RH, Hasanat MA.   +8 more
europepmc   +1 more source

Mesenchymal Stromal Cell‐Mediated Intercellular Communication: Mapping the Interactome for Skeletal Muscle Homeostasis and Regeneration

Advanced Science, EarlyView.
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu, Edgar E. Perez Carbajal, Yih‐Chii Hwang, Sahil A. Mapkar, Benjamin W. Gilman, Sarah A. Bliss, Lam B. Tran, Kalgi T. Mehta, Jacob O. Banyasz, Ming Yu, Reynold R. Liu, Matthew N. Ly, Christapher S. Morrissey, Michael N. Wosczyna   +13 more
wiley   +1 more source

Seeking the Mechanism for Reversal of Enhanced Insulin Sensitivity After Acute Exercise. [PDF]

Exerc Sport Sci Rev
Wang H, Cartee GD.
europepmc   +1 more source

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.

Journal of Clinical Investigation, 1995
G. Hotamisligil, P. Arner, J. Caro, R. Atkinson, B. Spiegelman   +4 more
semanticscholar   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Characterization and modulation of human insulin degrading enzyme conformational dynamics to control enzyme activity. [PDF]

Elife
Mancl JM, Liang WG, Bayhi NL, Wei H, Budell WC, Mendez JH, Sosnick TR, Carragher B, Potter CS, Potter CS, Tang WJ.   +10 more
europepmc   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source