Results 1 to 10 of about 4,590 (196)
Insulin Glargine and Insulin Aspart Overdose With Pharmacokinetic Analysis
: Objective: Insulin glargine is a long-acting insulin analogue with biotransformation, at the injection site, to a primary active metabolite (glargine-M1).
Christian C.K. Kim, MD+4 more
doaj +3 more sources
Cloning and Extracellular Expression of Glargine in Pichia pastoris
Patients with diabetes mellitus increase significantly every year. The increasing number of people with diabetes mellitus results in increased insulin requirements.
Dudi Hardianto+6 more
doaj +1 more source
Abstract There is an overweight/obesity crisis in both human and companion animal populations globally. Veterinarians have an ethical obligation to protect animal welfare and, therefore, have a duty to intervene by supporting their clients in changing care plans to mitigate and prevent pet overweight/obesity.
Jenny Lynden+2 more
wiley +1 more source
Highlights Metformin activates GDF15 expression, which reduces appetite with induction of weight loss in both diabetic and non‐diabetic patients. GDF15 level is linked and correlated with the progression of diabetic complications including thrombosis, diabetic nephropathy, diabetic neuropathy, and diabetic retinopathy. Abstract Type 2 diabetes mellitus
Hayder M. Al‐kuraishy+8 more
wiley +1 more source
Insulin glargine and cancer risk in patients with diabetes: a meta-analysis. [PDF]
AimThe role of insulin glargine as a risk factor for cancer is controversial in human studies. The aim of this meta-analysis was to evaluate the relationship between insulin glargine and cancer incidence.MethodsAll observational studies and randomized ...
Xulei Tang+3 more
doaj +1 more source
Comparison between basal insulin glargine and NPH insulin in patients with diabetes type 1 on conventional intensive insulin therapy [PDF]
Background/Aim. Insulin glargine is a long-acting insulin analog that mimics normal basal insulin secretion without pronounced peaks. The aim of this study was to compare insulin glargine with isophane insulin (NPH insulin) for basal insulin supply in ...
Pešić Milica+5 more
doaj +1 more source
In time, prescription of insulin therapy (IT) becomes inevitable for many patients with type 2 diabetes mellitus (DM) to achieve and maintain the target hypoglycemic range.According to the current guidelines, the addition of basal insulin to glucose ...
E. V. Biryukova+2 more
doaj +1 more source
In vitro metabolic and mitogenic signaling of insulin glargine and its metabolites. [PDF]
BACKGROUND: Insulin glargine (Lantus) is a long-acting basal insulin analog that demonstrates effective day-long glycemic control and a lower incidence of hypoglycemia than NPH insulin.
Mark R Sommerfeld+6 more
doaj +1 more source
Insulin glargine is a long-acting analogue of human insulin that has been used to manage hyperglycemia in patients with diabetes mellitus (DM) for nearly 20 years.
Parag Goyal+24 more
doaj +1 more source