Results 1 to 10 of about 4,590 (196)

Insulin Glargine and Insulin Aspart Overdose With Pharmacokinetic Analysis

open access: yesAACE Clinical Case Reports, 2016
: Objective: Insulin glargine is a long-acting insulin analogue with biotransformation, at the injection site, to a primary active metabolite (glargine-M1).
Christian C.K. Kim, MD   +4 more
doaj   +3 more sources

Cloning and Extracellular Expression of Glargine in Pichia pastoris

open access: yesHayati Journal of Biosciences, 2023
Patients with diabetes mellitus increase significantly every year. The increasing number of people with diabetes mellitus results in increased insulin requirements.
Dudi Hardianto   +6 more
doaj   +1 more source

Animal obesity: What insights can a one health approach offer when it comes to veterinarians ‘making every contact count’?

open access: yesVeterinary Record, Volume 191, Issue 11, 3/10 December 2022., 2022
Abstract There is an overweight/obesity crisis in both human and companion animal populations globally. Veterinarians have an ethical obligation to protect animal welfare and, therefore, have a duty to intervene by supporting their clients in changing care plans to mitigate and prevent pet overweight/obesity.
Jenny Lynden   +2 more
wiley   +1 more source

Metformin and growth differentiation factor 15 (GDF15) in type 2 diabetes mellitus: A hidden treasure 二甲双胍和生长分化因子15 (GDF15)在2型糖尿病中的作用:一个隐藏的宝藏

open access: yesJournal of Diabetes, Volume 14, Issue 12, Page 806-814, December 2022., 2022
Highlights Metformin activates GDF15 expression, which reduces appetite with induction of weight loss in both diabetic and non‐diabetic patients. GDF15 level is linked and correlated with the progression of diabetic complications including thrombosis, diabetic nephropathy, diabetic neuropathy, and diabetic retinopathy. Abstract Type 2 diabetes mellitus
Hayder M. Al‐kuraishy   +8 more
wiley   +1 more source

Insulin glargine and cancer risk in patients with diabetes: a meta-analysis. [PDF]

open access: yesPLoS ONE, 2012
AimThe role of insulin glargine as a risk factor for cancer is controversial in human studies. The aim of this meta-analysis was to evaluate the relationship between insulin glargine and cancer incidence.MethodsAll observational studies and randomized ...
Xulei Tang   +3 more
doaj   +1 more source

Comparison between basal insulin glargine and NPH insulin in patients with diabetes type 1 on conventional intensive insulin therapy [PDF]

open access: yesVojnosanitetski Pregled, 2007
Background/Aim. Insulin glargine is a long-acting insulin analog that mimics normal basal insulin secretion without pronounced peaks. The aim of this study was to compare insulin glargine with isophane insulin (NPH insulin) for basal insulin supply in ...
Pešić Milica   +5 more
doaj   +1 more source

Long-acting insulin analogue in the treatment of type 2 diabetes mellitus: emphasis on proven efficacy and safety

open access: yesМедицинский совет, 2021
In time, prescription of insulin therapy (IT) becomes inevitable for many patients with type 2 diabetes mellitus (DM) to achieve and maintain the target hypoglycemic range.According to the current guidelines, the addition of basal insulin to glucose ...
E. V. Biryukova   +2 more
doaj   +1 more source

In vitro metabolic and mitogenic signaling of insulin glargine and its metabolites. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND: Insulin glargine (Lantus) is a long-acting basal insulin analog that demonstrates effective day-long glycemic control and a lower incidence of hypoglycemia than NPH insulin.
Mark R Sommerfeld   +6 more
doaj   +1 more source

Physicochemical and functional characterization of MYL-1501D, a proposed biosimilar to insulin glargine.

open access: yesPLoS ONE, 2021
Insulin glargine is a long-acting analogue of human insulin that has been used to manage hyperglycemia in patients with diabetes mellitus (DM) for nearly 20 years.
Parag Goyal   +24 more
doaj   +1 more source

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