Results 71 to 80 of about 4,590 (196)
Therapeutic Advances in Endocrinology and Metabolism, 2012 The three currently marketed long-acting insulin analogs, glargine, detemir and insulin lispro protamine suspension (ILPS), represent the most significant advances in basal insulin supplementation since the 1940s and 1950s and the introduction of the ...
Dario Giugliano, Katherine Esposito
doaj +1 more source
Indian Journal of Endocrinology and Metabolism, 2014 Aim: To determine the safety and efficacy of biphasic insulin aspart 30 (BIAsp 30) therapy in the Indian patients with type 2 diabetes previously on basal or basal-bolus insulin therapies.
Arpandev Bhattacharyya +3 more
doaj +1 more source
Endocrinology, Diabetes &Metabolism, Volume 8, Issue 3, May 2025.Once‐daily insulin provides superior HbA1c reduction compared to once‐weekly insulin in type 1 diabetes, while fasting blood glucose levels remain comparable. Although once‐weekly insulin may improve adherence, it is associated with higher rates of injection site reactions and adverse events, requiring careful consideration of patient‐specific factors ...
Obieda Altobaishat +7 more
wiley +1 more source
A case of hypersensitivity to soluble and isophane insulins but not to insulin glargine
Indian Journal of Pharmacology, 2015 Insulin is an important agent for the treatment of diabetes mellitus (DM). Allergic reactions to insulin therapy, although rare, have been evident since animal insulin became available for the treatment of DM in 1922. Hypersensitivity to insulin has considerably been reduced with the introduction of human insulin produced by recombinant ...
Sarayu A. Pai +5 more
openaire +4 more sources
Synapse, Volume 79, Issue 3, May 2025.Synaptic vesicle glycoprotein 2A (SV2A) is a key marker of synaptic density and the target of UCB‐J PET radioligands. In rats with chronic hyperglycemia (glucose >13.8 mmol/L), [3H]UCB‐J binding and SV2A levels were significantly elevated in the cortex and hippocampus, alongside increased glutamate release, despite unchanged levels of other presynaptic
Burcu Azak Pazarlar +3 more
wiley +1 more source
Modeling and Optimization of Insulin Injection for Type-1 Diabetes Mellitus Management [PDF]
Diabetes mellitus is a global health crisis characterized by poor blood sugar regulation, impacting millions of people worldwide and leading to severe complications and mortality. Although Type 1 Diabetes Mellitus (T1DM) has a lower number of cases compared to other forms of diabetes, it is often diagnosed at a young age and requires lifelong exogenous
arxiv +1 more source
Diabetes, Obesity and Metabolism, Volume 27, Issue 5, Page 2485-2494, May 2025.Abstract Aims Managing type‐2 diabetes (T2D) in chronic kidney disease (CKD) patients requires consideration of kidney function, and many drugs have not been investigated thoroughly. Clinical studies have demonstrated Glargine U300 (Gla‐300) supports achievement of adequate glycemic control at low hypoglycemia risk.
Anjaly Vijayan +9 more
wiley +1 more source
ClinicoEconomics and Outcomes Research, 2020 Asrul Akmal Shafie,1 Chin Hui Ng2 1Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Penang, Malaysia; 2Pharmacy Department, Hospital Raja Permaisuri Bainun, Ipoh 30450, Perak, MalaysiaCorrespondence: Asrul Akmal ...
Shafie AA, Ng CH
doaj
The insulin superfamily of growth-promoting proteins [PDF]
arXiv, 2007 Recently, structural analysis of the human transferrin and growth hormone (GH) amino acid sequences has unravelled that they harbor a motif identical to a pattern found in viral oncoproteins known to bind the primarily nuclear tumor suppressor retinoblastoma protein (RB).
arxiv