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Gambaran Indeks Trigliserida dan Glukosa Pada Penyandang Obes

Majalah Kedokteran Andalas, 2022
TUJUAN: Penelitian bertujuan untuk mengetahui gambaran TyG-Index pada penyandang obes.   METODE: Penelitian ini menggunakan metode deskriptif analitik cross sectional terhadap subjek yang memenuhi kriteria IMT ≥25 kg/m2 dengan rentang usia 18-60 tahun.
mulyanti mul yanti
doaj   +1 more source

Estimation of insulin sensitivity from continuous glucose monitoring and insulin pump data in type 1 diabetes [PDF]

, 2012
Diabetes mellitus is a disease characterized by chronic hyperglycemia either due to a lack of secretion of the hormone insulin (Type 1 Diabetes Mellitus, T1DM) or due to impaired action of this hormone (Type 2 Diabetes Mellitus, T2DM).
Ronca, Gabriele
core  

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Validation of a novel index to assess insulin resistance of adipose tissue lipolytic activity in obese subjects

Journal of Lipid Research, 2012
Insulin resistance in adipose tissue increases the release of free fatty acids into the circulation, which likely contributes to impaired insulin action in liver and skeletal muscle associated with obesity.
Elisa Fabbrini, Faidon Magkos, Caterina Conte, Bettina Mittendorfer, Bruce W. Patterson, Adewole L. Okunade, Samuel Klein   +6 more
doaj   +1 more source

Data_Sheet_1_Non-insulin-based insulin resistance indices for predicting all-cause mortality and renal outcomes in patients with stage 1–4 chronic kidney disease: another paradox.docx

, 2023
Non-insulin-based insulin resistance (IR) indices serve as the indicators of metabolic syndrome (MetS) but have limited value for predicting clinical outcomes.
Sheng-Wen Niu (5439521), Chi-Chih Hung, Feng-Ching Shen, Jer-Ming Chang, Yu-Lin Chao, Yi-Kong Chen (15467132), Yu-Lin Chao (6653192), Jer-Ming Chang (106541), Yi-Kong Chen, I-Ching Kuo (4424632), Feng-Ching Shen (13808335), Hugo You-Hsien Lin (14110301), Sheng-Wen Niu, Chi-Chih Hung (106523), Hugo You-Hsien Lin, Wei-Chung Tsai, Wei-Chung Tsai (300077), I-Ching Kuo   +17 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Matsuda index adjusted for sustained hyperglycemia via propensity scores outperforms homeostatic model assessment for insulin resistance in identifying insulin—requiring gestational diabetes mellitus

SAGE Open Medicine
Background: Gestational diabetes mellitus, a glucose metabolism disorder during pregnancy, is linked to insulin resistance. Pregnancy elevates insulin resistance, and gestational diabetes mellitus increases fetal complication risks via excessive glucose ...
Mayuko Soma, Kuninori Iwayama, Chisa Takashina, Toshitaka Nakaya, Masahiro Tsuji, Ainari Konda, Maiko Machida   +6 more
doaj   +1 more source

Insulin therapy and dietary adjustments to normalize glycemia and prevent nocturnal hypoglycemia after evening exercise in type 1 diabetes: a randomized controlled trial [PDF]

, 2015
Introduction Evening-time exercise is a frequent cause of severe hypoglycemia in type 1 diabetes, fear of which deters participation in regular exercise.
Gonzalez, JT, Walker, Mark, Stevenson, Emma, Gonzalez, Javier T, Campbell, Matthew, Turner, David, Richard Bracken, Bracken, Richard M, Bracken, Richard, Shaw, James, Shaw, JA, West, Daniel J, Walker, M, Bracken, RM, Turner, Daniel, Stevenson, Emma J, Stevenson, EJ, Gonzalez, Javier, Campbell, MD, West, DJ, Turner, D, Shaw, James A, West, Dan   +22 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Predicting time to glycemic stability in hospitalized type 2 diabetes patients using insulin resistance indices: a nomogram development and validation study

Endocrine Connections
Background: Achieving rapid glycemic stability with intensive insulin therapy in hospitalized type 2 diabetes patients remains unpredictable. We hypothesized that the underlying insulin resistance is a key determinant of this response.
Ying Ke, Shasha Shi, Nan Zhou, Hongyuan Shi, Ming Zhang, Yi He, Haixia Liu, Xiaoyun Liu, Jing Jiang, Cuicui Lv, Nan Zhao   +10 more
doaj   +1 more source