Insulin hypoglycaemia test guided by a glucose controlled insulin infusion system [PDF]
Acta Endocrinologica, 1984 Abstract. Insulin hypoglycaemia test (IHT) for assessment of hypothalamic-pituitary-adrenocortical (HPA) function in patients with pituitary tumours is usually performed by bolus injection of insulin, a procedure which includes the risk of overdosage and/or the need of repeated administration.
Müller-Esch, G. +4 more
core +6 more sources
Continuous Drug Infusion for Diabetes Therapy: A Closed-Loop Control System Design [PDF]
EURASIP Journal on Wireless Communications and Networking, 2008 While a typical way for diabetes therapy is discrete insulin infusion based on long-time interval measurement, in this paper, we design a closed-loop control system for continuous drug infusion to improve the traditional discrete methods and make ...
Xiao Yang +4 more
doaj +3 more sources
In silico evaluation of a control system and algorithm for automated insulin infusion in the ICU setting [PDF]
BioMedical Engineering OnLine, 2010 Background It is known that tight control of glucose in the Intensive Care Unit reduces morbidity and mortality not only in diabetic patients but also in those non-diabetics who become transiently hyperglycemic.
Olmos Pablo R +3 more
doaj +3 more sources
An Insulin Infusion Advisory System Based on Autotuning Nonlinear Model-Predictive Control
IEEE Transactions on Biomedical Engineering, 2011 This paper aims at the development and evaluation of a personalized insulin infusion advisory system (IIAS), able to provide real-time estimations of the appropriate insulin infusion rate for type 1 diabetes mellitus (T1DM) patients using continuous ...
Konstantina Nikita +2 more
exaly +2 more sources
Intralipid decreases apolipoprotein M levels and insulin sensitivity in rats. [PDF]
PLoS ONE, 2014 BACKGROUND: Apolipoprotein M (ApoM) is a constituent of high-density lipoproteins (HDL). It plays a crucial role in HDL-mediated reverse cholesterol transport. Insulin resistance is associated with decreased ApoM levels.
Lu Zheng +10 more
doaj +1 more source
Development of Individual Insulin Infusion Profiles for Open Loop Infusion Systems [PDF]
Hormone and Metabolic Research, 1984 The computer program for the open loop infusion device simulated the feed-back structure of a closed loop insulin secretion control by an algorithm based upon a theoretical postprandial blood sugar profile. Fifteen unstable juvenile onset insulin requiring diabetics could be well controlled after two to three days of an intravenous open loop insulin ...
Strack, Thomas +5 more
openaire +3 more sources
Effects of somatostatin added to insulin in a glucose-controlled insulin infusion system [PDF]
Diabetologia, 1981 Five insulin treated diabetics were studied on three consecutive days. Overnight variable intravenous insulin infusions were used before each study to maintain normoglycaemia and to calculate the optimal basal insulin infusion rate (1.1 +/- 0.1 U/h) which ws then kept constant throughout the study day. A standard 400 kCal breakfast with 25 g xylose was
J L, Selam +8 more
openaire +2 more sources
Clinical and cost-effectiveness of continuous subcutaneous insulin infusion for diabetes [PDF]
, 2004 Objectives: To assess the clinical and cost-effectiveness of continuous subcutaneous insulin infusion (CSII) compared with multiple daily injections (MDI) in the delivery of intensive insulin therapy for the treatment of diabetes mellitus.
Green, C. +9 more
core +1 more source
Annals of Intensive Care, 2017 Background Glucose control is an important issue in post-operative patients. The objective here was to compare two insulin infusion lines by syringe pumps to assess the impact of medical devices on glycaemic variability in surgical patients under ...
Stéphanie Genay +9 more
doaj +1 more source
Investigation of stability in a two-delay model of the ultradian oscillations in glucose-insulin regulation [PDF]
, 2015 In this paper, a two-delay model for the ultradian oscillatory behaviour of the glucose-insulin regulation system is studied. Hill functions are introduced to model nonlinear physiological interactions within this system and ranges on parameters ...
Easton, Jonathan +2 more
core +1 more source