LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li +12 more
wiley +1 more source
Device Insertion Versus Material: Drivers of Inflammation in Diabetes Device Interfaces. [PDF]
Cunegundes PS +5 more
europepmc +1 more source
Development of more complex in vitro models necessitates the development of improved monitoring approaches. This work demonstrates a novel conformable device capable of measuring the resistance of two cell barriers within a single model independently, a significant advantage over conventional trans‐epithelial/endothelial electrical resistance (TEER ...
Alexandra Elisabeth Wheeler +7 more
wiley +1 more source
Comparison of oral versus intravenous glucose exposure on plasma growth hormone levels: a crossover study in healthy volunteers. [PDF]
Vinten AK +4 more
europepmc +1 more source
Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du +5 more
wiley +1 more source
16. Diabetes Care in the Hospital: Standards of Care in Diabetes-2026. [PDF]
American Diabetes Association Professional Practice Committee for Diabetes* .
europepmc +1 more source
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao +36 more
wiley +1 more source
Successful rapid desensitization to multiple insulin preparations in an adult with type 1 diabetes: a case report and literature review. [PDF]
Chen Y, Zhu W, Chen G, Yao J.
europepmc +1 more source
Simplified evaluation and documentaion of data from glucose-controlled insulin infusion Systems: Part. II: Artefact handling [PDF]
Müller-Esch, G. +2 more
core +1 more source
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang +9 more
wiley +1 more source

