Coloured Petri Nets-Based Modeling and Validation of Insulin Infusion Pump Systems
Safety and effectiveness are crucial quality attributes for insulin infusion pump systems. Therefore, regulatory agencies require the quality evaluation and approval of such systems before the market to decrease the risk of harm, motivating the usage of ...
Tássio Fernandes Costa +4 more
doaj +1 more source
Best Achievements in Clinical Medicine in Diabetes and Dyslipidemia in 2020 [PDF]
Over the last two decades, our understanding of diabetes and treatment strategies have evolved tremendously, from scientific, mechanistic, and human perspectives.
Eun-Jung Rhee +2 more
doaj +1 more source
Insulin hypoglycaemia test guided by a glucose controlled insulin infusion system [PDF]
Abstract. Insulin hypoglycaemia test (IHT) for assessment of hypothalamic-pituitary-adrenocortical (HPA) function in patients with pituitary tumours is usually performed by bolus injection of insulin, a procedure which includes the risk of overdosage and/or the need of repeated administration.
Müller-Esch, G. +4 more
openaire +3 more sources
Dynamic Insulin Basal Needs Estimation and Parameters Adjustment in Type 1 Diabetes
Technology advances have made possible improvements such as Continuous Glucose Monitors, giving the patient a glucose reading every few minutes, or insulin pumps, allowing more personalized therapies.
Jesús Berián +4 more
doaj +1 more source
Effects of somatostatin added to insulin in a glucose-controlled insulin infusion system [PDF]
Five insulin treated diabetics were studied on three consecutive days. Overnight variable intravenous insulin infusions were used before each study to maintain normoglycaemia and to calculate the optimal basal insulin infusion rate (1.1 +/- 0.1 U/h) which ws then kept constant throughout the study day. A standard 400 kCal breakfast with 25 g xylose was
J L, Selam +8 more
openaire +2 more sources
Mast Cell Deficiency in Mice Attenuates Insulin Phenolic Preservative-Induced Inflammation
One major obstacle that limits the lifespan of insulin infusion pumps is surmounting the tissue site reaction at the device implantation site. All commercial insulin formulations contain insulin phenolic preservatives (IPPs) designed to ensure insulin ...
Shereen Kesserwan +3 more
doaj +1 more source
Real-World Analysis of Therapeutic Outcome in Type 1 Diabetes Mellitus at a Tertiary Care Center [PDF]
Insulin replacement in type 1 diabetes mellitus (T1DM) needs intensified treatment, which can either be performed by multiple daily injections (MDI) or continuous subcutaneous insulin infusion (CSII).
Antonia Kietaibl +2 more
doaj +1 more source
The goal in type 1 diabetes (T1D) therapy is to maintain optimal glycemic control under any circumstance. Diabetes technology is in continuous development to achieve this goal. The most advanced Food and Drug Administration- and European Medicines Agency-
Jesus Dominguez-Riscart +9 more
doaj +1 more source
Transient Neonatal Diabetes Mellitus Managed with Continuous Subcutaneous Insulin Infusion (CSII) and Continuous Glucose Monitoring [PDF]
Neonatal diabetes mellitus can be categorized as transient, permanent, or syndromic, and approximately half of the cases are transient. We present a case involving a term newborn who showed overt progression of transient neonatal diabetes mellitus, with ...
Min Soo Kim +9 more
doaj +1 more source
Improving the clinical value and utility of CGM systems: issues and recommendations : a joint statement of the European Association for the Study of Diabetes and the American Diabetes Association Diabetes Technology Working Group [PDF]
The first systems for continuous glucose monitoring (CGM) became available over 15 years ago. Many then believed CGM would revolutionise the use of intensive insulin therapy in diabetes; however, progress towards that vision has been gradual.
Bergenstal, Richard M. +5 more
core +4 more sources

