Circulating vaspin is unrelated to insulin sensitivity in a cohort of nondiabetic humans [PDF]
Objective: To study the association of vaspin with glucose metabolism. Design: Cross-sectional and intervention study. Subjects and methods: The association of serum vaspin with metabolic and anthropometric characteristics was investigated in 108
Isken, Frank +8 more
core +1 more source
소아청소년 1형 당뇨병 환자에서 연속혈당측정기와 인슐린펌프의 사용
Type 1 diabetes requires lifelong insulin therapy because insulin-secretion capability is diminished. Glycemic control and glucose monitoring are important to prevent type 1 diabetes complications. Diabetes technologies have developed rapidly; continuous
doaj +1 more source
Free fatty acids link metabolism and regulation of the insulin-sensitizing fibroblast growth factor-21 [PDF]
OBJECTIVE—Fibroblast growth factor (FGF)-21 improves insulin sensitivity and lipid metabolism in obese or diabetic animal models, while human studies revealed increased FGF-21 levels in obesity and type 2 diabetes.
Pfeiffer, Andreas F. H. +29 more
core +1 more source
Current Advances of Artificial Pancreas Systems: A Comprehensive Review of the Clinical Evidence [PDF]
Since Banting and Best isolated insulin in the 1920s, dramatic progress has been made in the treatment of type 1 diabetes mellitus (T1DM). However, dose titration and timely injection to maintain optimal glycemic control are often challenging for T1DM ...
Sun Joon Moon +2 more
doaj +1 more source
Clinical effectiveness and cost-effectiveness of continuous subcutaneous insulin infusion for diabetes : systematic review and economic evaluation [PDF]
Based on the totality of evidence, using observational studies to supplement the limited data from randomised trials against best MDI, CSII provides some advantages over MDI in T1DM for both children and adults.
P Royle +13 more
core +1 more source
Management and efficacy of intensified insulin therapy starting in outpatients [PDF]
Diabetic patients under multiple injection insulin therapy (i.e., intensified insulin therapy, IIT) usually start this treatment during hospitalization. We report here on the logistics, efficacy, and safety of IIT, started in outpatients.
Winkelmann, W. +11 more
core +1 more source
Background: Glucagon leads to substantial but short-lived subcutaneous vasodilation. Using micro-amounts of glucagon at the insulin injection site increases insulin absorption.
Ilze Dirnena-Fusini, PhD +3 more
doaj +1 more source
The role of technology in the care of diabetes mellitus in pregnancy: an expert review
Diabetes mellitus is one of the most commonly encountered pregnancy complications and is associated with multiple adverse perinatal outcomes. Technology has progressed to address the unique challenges patients face in managing diabetes mellitus in ...
Sydney M. Thayer, MD +2 more
doaj +1 more source
The role of insulin receptor substrate 2 in hypothalamic and β cell function [PDF]
Insulin receptor substrate 2 (Irs2) plays complex roles in energy homeostasis. We generated mice lacking Irs2 in β cells and a population of hypothalamic neurons (RIPCreIrs2KO), in all neurons (NesCreIrs2KO), and in proopiomelanocortin neurons ...
Hisadome, Kazunari +59 more
core +1 more source
Use of continuous subcutaneous insulin infusion by a portable insulin pump during pregnancy in women with type 1 diabetes mellitus [PDF]
Background/aim: Diabetes mellitus is associated with an increased risk for neonatal morbidity and mortality. One of the most important goals in treating pregnancies complicated with diabetes is keeping glucose level within the normal range, especially in
Zorić Svetlana +8 more
doaj +1 more source

