A review of insulin lispro for the treatment of patients with type 2 diabetes mellitus [PDF]
Сахарный диабет, 2016 A critical aspect of the treatment of most patients with type 2 diabetes mellitus (T2DM) is the initiation (and subsequent intensification) of insulin therapy when lifestyle interventions and oral anti-hyperglycaemic drugs fail to maintain or improve ...
Marina V. Shestakova +2 more
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Safety of Insulin Lispro and a Biosimilar Insulin Lispro When Administered Through an Insulin Pump. [PDF]
J Diabetes Sci Technol, 2018 Background: SAR342434 (U100; SAR-Lis; insulin lispro) is a biosimilar/follow-on to insulin lispro (U100; Ly-Lis). Similar pharmacokinetics/pharmacodynamics between the two products has been demonstrated in a hyperinsulinemic euglycemic clamp study.
Thrasher J +6 more
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Exenatide versus Insulin Lispro Added to Basal Insulin in a Subgroup of Korean Patients with Type 2 Diabetes Mellitus [PDF]
Diabetes & Metabolism Journal, 2017 BackgroundThe prevalence of type 2 diabetes mellitus (T2DM) and obesity is increasing in Korea. Clinical studies in patients with T2DM have shown that combining the glucagon-like peptide-1 receptor agonist exenatide twice daily with basal insulin is an ...
Kun-Ho Yoon, Elise Hardy, Jenny Han
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Diabetes, Metabolic Syndrome and Obesity, 2012 J Uy, L Fogelfeld, Y GuerraDivision of Endocrinology, Diabetes and Metabolism, John H Stroger Jr Hospital of Cook County, Chicago; Department of Endocrinology, Diabetes and Metabolism, Rush University Hospital, Chicago, IL, USAAbstract: We have now at ...
Uy J, Fogelfeld L, Guerra Y
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Ultra rapid lispro improves postprandial glucose control versus lispro in combination with basal insulin: a study based on CGM in type 2 diabetes in China [PDF]
Frontiers in EndocrinologyAimTo evaluate the efficacy and safety of URLi (ultra rapid lispro insulin) compared to insulin lispro as bolus insulin with basal insulin using CGM in the individuals with type 2 diabetes(T2D) in China.MethodsThis was a double-blind, randomized ...
Lu Yuan +6 more
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The human insulin analogue insulin lispro
Annals of Medicine, 1998 Insulin lispro is a newly developed analogue of human insulin where the positions of the amino acids lysine and proline have been switched at the end of the B chain of the insulin molecule. Insulin lispro with lysine at position B28 and proline at position B29 has a weaker tendency for self-association than human insulin.
Veikko A Koivisto, V A Koivisto
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Anti-Insulin Antibodies and Adverse Events with Biosimilar Insulin Lispro Compared with Humalog Insulin Lispro in People with Diabetes. [PDF]
Diabetes Technol Ther, 2018 \ua9 Philip Home, et al., 2018; Published by Mary Ann Liebert, Inc. 2018. Background: SAR342434 (SAR-Lis) is a biosimilar (follow-on) of insulin lispro (Humalog\uae; Ly-Lis).
Home P +6 more
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CamAPS FX hybrid closed-loop with ultra-rapid lispro compared with standard lispro in adults with type 1 diabetes: a double-blind, randomized, crossover study. [PDF]
, 2023 INTRODUCTION To evaluate hybrid closed-loop with ultra-rapid insulin lispro (Lyumjev) compared with hybrid closed-loop with standard insulin lispro in adults with type 1 diabetes.
Evans, Mark +9 more
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PLoS ONE, 2021 BackgroundGlucocorticoid (GC)-exacerbated hyperglycemia is prevalent in hospitalized patients with diabetes mellitus (DM) but evidence-based insulin guidelines in inpatient settings are lacking.Methods and findingsRetrospective cohort study with ...
Yu-Chien Cheng +6 more
doaj +1 more source
4S-fluorination of ProB29 in insulin lispro slows fibril formation. [PDF]
J Biol ChemOpen access article. Creative Commons Attribution 4.0 International license (CC BY 4.0) appliesRecombinant insulin is a life-saving therapeutic for millions of patients affected by diabetes mellitus. Standard mutagenesis has led to insulin variants with
Breunig SL +8 more
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