Results 61 to 70 of about 412,643 (184)

Better Glycemic Control with Insulin Premix 50/50 TID Compared to Insulin Premix 70/30 BID - Original Article

Endocrinology Research and Practice, 2010
Objective: Since only a small proportion of diabetics achieve optimal glycemic targets, intensification of treatment with insulin is needed in most of the cases. Application of insulin lispro premix 50/50 TID provides better glycemic control compared to
Hasan Aydın
doaj   +2 more sources

Damping amyloid‐associated conformational fluctuations in a protein by an engineered diselenide bridge

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Polypeptide cross‐β assembly, characteristic of diverse proteotoxic diseases, defines a general thermodynamic ground state and limits the shelf lives of peptide‐ and protein therapeutics. A model is provided by insulin. Although the hormone contains a predominance of α‐helix, its fibrils exhibit cross‐β reorganization.
Yanwu Yang, Balamurugan Dhayalan, Andreas Ehnbom, Orit Weil‐Ktorza, Norman Metanis, Michael A. Weiss   +5 more
wiley   +1 more source

GIP in Cardiovascular and Kidney Disease: From Physiology to Pharmacology

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6509-6532, August 2026.
ABSTRACT Aims To provide a comprehensive overview of the cardiovascular and renal effects of glucose‐dependent insulinotropic polypeptide (GIP) by integrating its physiological role with recent human trial data on tirzepatide, the first dual GIP and glucagon‐like peptide‐1 (GLP‐1) receptor agonist.
Michelantonio De Fano, Line L. Haurum, Christine R. Schwarz, Francesca Porcellati, Andreas Andersen   +4 more
wiley   +1 more source

Atenção farmacêutica ao paciente diabético tipo 1 em uso de insulina [PDF]

, 2014
Trabalho apresentado no 31º SEURS - Seminário de Extensão Universitária da Região Sul, realizado em Florianópolis, SC, no período de 04 a 07 de agosto de 2013 - Universidade Federal de Santa Catarina.O diabetes mellitus (DM) é uma doença caracterizada ...
Daher, Josélia, Garabeli, Aline
core  

Treatment satisfaction and quality of life with insulin glargine plus insulin lispro compared with NPH insulin plus unmodified human insulin in individuals with type 1 diabetes

OBJECTIVE - The purpose of this study was to compare quality of life (QoL) and treatment satisfaction using insulin glargine plus insulin lispro with that using NPH insulin plus unmodified human insulin in adults with type 1 diabetes managed with ...
Ashwell SG, Witthaus E, Stephens JW, Home PD, Bradley C   +4 more
core   +5 more sources

A simple dilute and shoot methodology for the identification and quantification of illegal insulin

Journal of Pharmaceutical Analysis, 2016
The occurrence of illegal medicines is a well-established global problem and concerns mostly small molecules. However, due to the advances in genomics and recombinant expression technologies there is an increased development of polypeptide therapeutics ...
Celine Vanhee, Steven Janvier, Goedele Moens, Eric Deconinck, Patricia Courselle   +4 more
doaj   +1 more source

Efficacy of Russian insulin biosimilars for type 1 diabetes in adolescents [PDF]

РМЖ. Мать и дитя, 2022
V.V. Platonov1,2, T.A. Dubinina1, E.M. Patrakeeva3, A.M. Rezvykh2, N.V. Kazachenko1 1K.A. Raukhfus Children’s City Multidisciplinary Clinical Center of High Medical Technologies,    St. Peterburg, Russian Federation 2St. Petersburg
V.V. Platonov, T.A. Dubinina, E.M. Patrakeeva, A.M. Rezvykh, N.V. Kazachenko   +4 more
doaj  

Continuous glucose monitoring–guided management of capivasertib‐associated hyperglycemia: A case series of three patients

Journal of Diabetes Investigation, Volume 17, Issue 8, Page 1432-1437, August 2026.
Continuous glucose monitoring (CGM) visualized cyclic glycemic fluctuations associated with the 4‐days‐on/3‐days‐off capivasertib schedule. Compared with off‐treatment days, dosing days showed higher mean sensor glucose, greater coefficient of variation (CV), more time above 250 mg/dL, and lower time in range (TIR; 70–180 mg/dL).
Hiroki Okumura, Ryotaro Bouchi, Kenju Ando, Hannah Mizuno, Hirofumi Sugimoto, Kotaro Umamoto, Noriko Kodani, Noriko Ihana‐Sugiyama, Kazuo Izumi, Mitsuru Ohsugi, Kohjiro Ueki, Akihiko Shimomura, Chikako Shimizu, Akiyo Tanabe   +13 more
wiley   +1 more source

Cost-effectiveness of insulin analogs from the perspective of the Brazilian public health system

Brazilian Journal of Pharmaceutical Sciences, 2017
Human insulin is provided by the Brazilian Public Health System (BPHS) for the treatment of diabetes, however, legal proceedings to acquire insulin analogs have burdened the BPHS health system.
Maurílio de Souza Cazarim, João Paulo Vilela Rodrigues, Estael Luzia Coelho da Cruz-Cazarim, Lorena Rocha Ayres, Leonardo Régis Leira Pereira   +4 more
doaj   +1 more source

Hypoglycemic treatment of diabetic patients in the Emergency Department [PDF]

Farmacia Hospitalaria, 2016
Objectives: To analyze if the hypoglycemic therapy prescribed in the Emergency Department adapts to the consensus recommendations available, as well as to assess its clinical impact.
Carmen Caballero Requejo, Elena Urbieta Sanz, Abel Trujillano Ruiz, Celia García-Molina Sáez, María Onteniente Candela, Pascual Piñera Salmerón   +5 more
doaj   +1 more source