A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen +13 more
wiley +1 more source
NEW TECHNOLOGIES FOR THE TREATMENT OF TYPE I DIABETES DURING PREGNANCY
New technologies are opening up promising opportunities for the treatment of type I diabetes during pregnancy. Recent evidence suggests that continuous glucose monitoring (CGM) should be offered to all women receiving intensive insulin therapy early in ...
Ольга Ивановна Мищенко +7 more
doaj
Risk Factors for Discontinuation of Insulin Pump Therapy in Pediatric and Young Adult Patient Groups [PDF]
Karel Kostev +5 more
openalex +1 more source
3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley +1 more source
History of the development of insulin pump therapy technology
The twentieth century marked a golden age for endocrinology, particularly in the methods used to treat type 1 diabetes mellitus. One of the most significant advancements during this period was the development of the insulin pump.
Pavel A. Kazaryan +3 more
doaj +1 more source
Effects of Performing Morning Versus Afternoon Exercise on Glycemic Control and Hypoglycemia Frequency in Type 1 Diabetes Patients on Sensor-Augmented Insulin Pump Therapy [PDF]
Ana María Gómez +6 more
openalex +1 more source
The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo +5 more
wiley +1 more source
Andrea Tumminia,1 Laura Sciacca,1 Lucia Frittitta,1 Sebastiano Squatrito,1 Riccardo Vigneri,2 Rosario Le Moli,1 Letizia Tomaselli2 1Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Hospital ...
Tumminia A +6 more
doaj
Advantages of sensor-augmented insulin pump therapy for pregnant women with type 1 diabetes mellitus. [PDF]
Imafuku H +12 more
europepmc +1 more source
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang +3 more
wiley +1 more source

