Results 191 to 200 of about 222,467 (377)

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Advanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai   +15 more
wiley   +1 more source

Assessing attitudes towards insulin pump therapy in adults with type 1 diabetes: Italian validation of the Insulin Pump Attitudes Questionnaire (IT-IPA questionnaire). [PDF]

Acta Diabetol, 2023
Messina R, Indelicato L, Iommi M, Trombetta M, Roos T, Hermanns N, Di Sipio A, Fantini MP, Calvo V.   +8 more
europepmc   +1 more source

Glucose-Insulin-Potassium Therapy Guided by a Glucose-Controlled Insulin Infusion System in Acute Myocardinal Infarction [PDF]

, 1985
Ball, P., Bekemeyer, U., Djonlagic, H., Hauptmann, A., Heidbüchel, K., Müller-Esch, G., Osswald, P. M., Peters, A., Scriba, Peter Christian, Tybussek, R., Wood, W. G.   +10 more
core   +1 more source

Piperazine‐Functionalized Nanoparticles Enable Oral Insulin Delivery in Obese Mice

Advanced Science, EarlyView.
ABSTRACT Biologics have gained prominence as a rapidly advancing therapeutic modality for a diverse spectrum of medical conditions. Nonetheless, they are predominantly administered parenterally due to poor absorption through the gastrointestinal tract. Additionally, repeated injections of biologics such as insulin cause injection pain, leading to dose ...
Yuxue Cao, Xiaofan Jiang, Md Moniruzzaman, Alexandra Mueller, Taskeen Iqbal Janjua, Nisha Tyagi, Zhi Qu, Kuan Yau Wong, Yuran Feng, Aayushi Ghodasara, Ekaterina Strounina, Benjamin P. Ross, Tushar Kumeria, Sumaira Z. Hasnain, Amirali Popat   +14 more
wiley   +1 more source

Early Detection of Infusion Set Failure During Insulin Pump Therapy in Type 1 Diabetes [PDF]

, 2016
Marzia Cescon, Daniel J. DeSalvo, Trang T. Ly, David M. Maahs, Laurel H. Messer, Bruce A. Buckingham, Francis J. Doyle, Eyal Dassau   +7 more
openalex   +1 more source

Cockroach‐Derived Leucokinin VIII Peptide Accelerates Diabetic Skin Wound Healing by Enhancing Keratinocyte Filopodia Formation

Advanced Science, EarlyView.
This study identifies the cockroach‐derived peptide leucokinin VIII as a potent accelerator of diabetic wound healing. By activating the FAK‐ACTG1 axis, the peptide drives keratinocyte migration and filopodia formation. Delivered via a developed PLGA‐PEG‐PLGA thermosensitive hydrogel for sustained release, this approach significantly hastens wound ...
Zhengshan Qin, Jinchuan Wu, Xiehua Xiao, Xirui Wang, Nianhui Ding, Xin Zhao, Lu Ma, Jie Li, Lunkun Ma, Cehua Ou, Ning Ma, Jianguo Feng   +11 more
wiley   +1 more source

A Case of Lipoatrophy With Lispro Insulin Without Insulin Pump Therapy [PDF]

, 2004
Alfonso Arranz, Victor Andía, Antonio López-Guzmán   +2 more
openalex   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

The Effectiveness of Insulin Pump Therapy Versus Multiple Daily Injections in Children With Type 1 Diabetes Mellitus in a Specialized Center in Riyadh. [PDF]

Clin Med Insights Endocrinol Diabetes, 2022
Babiker A, Alammari N, Aljuraisi A, Alharbi R, Alqarni H, Masuadi E, Alfaraidi H.   +6 more
europepmc   +1 more source

Safety and Efficacy of Sustained Automated Insulin Delivery Compared to Sensor and Pump Therapy in Adults with Type 1 Diabetes at High Risk for Hypoglycemia: A Randomized Controlled Trial.

, 2023
Éric Renard, Michaël Joubert, Orianne Villard, Bleuenn Dreves, Yves Reznik, Anne Farret, J. Place, Marc D. Breton, Boris Kovatchev   +8 more
openalex   +1 more source