Results 41 to 50 of about 52,444 (287)

The Impact of a Pure Protein Load on the Glucose Levels in Type 1 Diabetes Patients Treated with Insulin Pumps

open access: yesInternational Journal of Endocrinology, 2015
We aimed to estimate the impact of ingestion of a pure protein load on the glucose levels in T1DM patients treated with insulin pumps. We examined 10 T1DM patients (6 females, mean age—32.3 years, mean HbA1c—6.8%) treated with insulin pumps equipped with
Tomasz Klupa   +4 more
doaj   +1 more source

Insulin Therapy is Associated With Increased Myocardial Interstitial Fibrosis and Cardiomyocyte Apoptosis in a Rodent Model of Experimental Diabetes

open access: yesFrontiers in Physiology, 2022
The incidence of diabetes mellitus (DM) is rising. DM is a risk factor for developing left ventricular (LV) dysfunction and adverse cardiovascular outcomes. Insulin, commonly used to treat DM, is associated with further worsening of such outcomes.
Fadi W. Adel   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

From bench to bedside: Tracing the payback forwards from basic or early clinical research – A preliminary exercise and proposals for a future study [PDF]

open access: yes, 2010
EXECUTIVE SUMMARY Chapter 1 : Introduction • The members of the research team from HERG and the Wellcome Trust have conducted previous studies showing that it is possible both to assess the payback from applied health research, and to use bibliometrics
Buxton, MJ   +4 more
core  

Management and efficacy of intensified insulin therapy starting in outpatients [PDF]

open access: yes, 1989
Diabetic patients under multiple injection insulin therapy (i.e., intensified insulin therapy, IIT) usually start this treatment during hospitalization. We report here on the logistics, efficacy, and safety of IIT, started in outpatients.
A Marble   +24 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Leeno: Type 1 diabetes management training environment using smart algorithms

open access: yesPLoS ONE, 2022
A growing number of Type-1 Diabetes (T1D) patients globally use insulin pump technologies to monitor and manage their glucose levels. Although recent advances in closed-loop systems promise automated pump control in the near future, most patients ...
Mohamed Raef Smaoui, Ahmad Lafi
doaj   +2 more sources

The use of insulin pumps as an innovative approach of diabetes therapy to improve glycemic control, patients' comfort of life and daily activity.

open access: yesJournal of Education, Health and Sport
Introduction and Purpose of Research. There are diverse types of insulin pumps available, such as traditional pumps with tubing, tubeless pumps or continuous glucose monitoring (CGM) systems, pumps with automated insulin suspension.
Patrycja Łazicka   +2 more
doaj   +1 more source

Parent Satisfaction with Diabetes Technology in Children with Type 1 Diabetes Mellitus [PDF]

open access: yes, 2014
Purpose: To increase glucose control, advanced technologies are being integrated into diabetes self-management in children with Type 1 Diabetes Mellitus (T1DM).
Carter, Laura Brooke
core   +1 more source

Optimal Regulation of Blood Glucose Level in Type I Diabetes using Insulin and Glucagon

open access: yes, 2019
The Glucose-Insulin-Glucagon nonlinear model [1-4] accurately describes how the body responds to exogenously supplied insulin and glucagon in patients affected by Type I diabetes.
Della Rossa, Fabio   +4 more
core   +4 more sources

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