Results 181 to 190 of about 744,871 (360)

Evidence that Receptor Aggregation may Play a Role in Transmembrane Signaling through the Insulin-Like Growth Factor-I Receptor [PDF]

, 1988
Nobuhiko Ikari, Hiroko Yoshino, Alan C. Moses, Jeffrey S. Flier   +3 more
openalex   +1 more source

Cytokine Engineering Approaches for Regenerative Medicine

Advanced Therapeutics, EarlyView.
Engineered cytokines represent a powerful strategy to promote tissue repair and regeneration by precisely modulating immune responses. This review highlights recent advances in cytokine engineering, including strategies to enhance half‐life, improve tissue and cell targeting, and control receptor signaling.
Shiyi Li, Wenhao You, Mikaël M. Martino
wiley   +1 more source

Multiscale Computational Protocols for Accurate Residue Interactions at the Flexible Insulin-Receptor Interface. [PDF]

J Chem Inf Model
Yurenko YP, Muždalo A, Černeková M, Pecina A, Řezáč J, Fanfrlík J, Žáková L, Jiráček J, Lepšík M.   +8 more
europepmc   +1 more source

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

Direct method for detection and characterization of cell surface receptors for insulin by means of 125I-labeled autoantibodies against the insulin receptor.

, 1976
David B. Jarrett, Jesse Roth, C. Ronald Kahn, J S Flier   +3 more
openalex   +1 more source

Novel Function for Endothelial Protease-Activated Receptors in Modulating Insulin Receptor Activity With Implications for Diabetes. [PDF]

Arterioscler Thromb Vasc Biol
Rajala R, Griffin CT.
europepmc   +1 more source

XBP1s Mediates Cross‐resistance to Combination Treatment of CDK4/6 Inhibitors plus Endocrine Therapy in Breast Cancer

Advanced Science, EarlyView.
Elevated spliced form of X‐box–binding protein 1 (XBP1) correlates with unfavorable responses to endocrine therapy plus CDK4/6 inhibitors in HR+/HER2− advanced breast cancer. XBP1s facilitates cell proliferation and G1/S transition by transcriptionally activating SND1, thereby activating the E2F1 pathway.
Yuting Sang, Shiyang Liu, Xujie Zhou, Weiru Chi, Min Xiong, Ming Chen, Hengyu Ren, Douwaner Liu, Liyi Zhang, Jingyan Xue, Yayun Chi, Jiong Wu   +11 more
wiley   +1 more source

Regulation of Hepatic Glycogen Synthesis During Fetal Development: Roles of Hydrocortisone, Insulin, and Insulin Receptors

, 1973
Howard J. Eisen, Ira D. Goldfine, Walter H. Glinsmann   +2 more
openalex   +1 more source

Mechanisms of insulin resistance in human obesity: evidence for receptor and postreceptor defects. [PDF]

, 1980
Orville Kolterman, J Insel, Mark Saekow, Jerrold M. Olefsky   +3 more
openalex   +1 more source

Identifying antisense oligonucleotides for targeted inhibition of insulin receptor isoform A. [PDF]

Front Oncol
Galifi CA, Dikdan RJ, Kantak D, Bulatowicz JJ, Maingrette K, Gunderson SI, Wood TL.   +6 more
europepmc   +1 more source