Advanced Science, EarlyView.During renal fibrosis, SMAD3 acts as a transcription factor for CRLF1, promoting its expression and secretion. CRLF1 then binds to ITGB1 via an autocrine mechanism, activating the PI3K‐AKT signaling pathway to mediate renal fibrosis. This accelerates the progression from AKI to CKD, highlighting the therapeutic potential of targeting CRLF1 for ...
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An update of contemporary insulin therapy. [PDF]
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Insulin Therapy for Acute Pancreatitis in a Patient With Lipase Maturation Factor 1 Mutation: A Case Report. [PDF]
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Glycemic Control and Quality of Life Among People with Type 1 Diabetes: Relationships with Insulin Therapy and Carbohydrate Counting. [PDF]
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