A propósito de un caso : paciente con cuadro de disartria de una hora y media de evolución [PDF]
Insulinoma is a neoplasia of pancreatic β-cells that secretes insulin. It constitutes a rare cause of hypoglycemia. Poor knowledge of this disease is explained by the low incidence, 4 in 1 million people per year. The nonspecific symptoms and its size
Roldán Vásquez, Ana María
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An unusual cause of hypoglycemia in a middle-aged female after bariatric surgery [PDF]
Non-insulinoma pancreatogenous hypoglycemia syndrome (NIPHS) is a disorder characterized by postprandial hypoglycemia and islet cell hypertrophy. It is an uncommon complication of weight-loss surgery.
Ahmed Salman +3 more
core +1 more source
ABSTRACT An adult dog presented for evaluation of a stuporous state following the ingestion of more than 50 xylitol‐containing chewing gums (minimum xylitol dose ingested > 3 mg/kg). On admission, the patient was hyperglycemic (9.0 mmol/L [163 mg/dL]) with moderately increased liver parameters and a normal plasma ammonia concentration.
Laurence M. Saint‐Pierre +3 more
wiley +1 more source
Benzbromarone, Quercetin, and Folic Acid Inhibit Amylin Aggregation [PDF]
Human Amylin, or islet amyloid polypeptide (hIAPP), is a small hormone secreted by pancreatic-cells that forms aggregates under insulin deficiency metabolic conditions, and it constitutes a pathological hallmark of type II diabetes mellitus.
Carrodeguas Villar, José Alberto +6 more
core +3 more sources
Pro-inflammatory cytokines attenuate glucose-stimulated insulin secretion from INS-1E insulinoma cells by restricting mitochondrial pyruvate oxidation capacity - Novel mechanistic insight from real-time analysis of oxidative phosphorylation. [PDF]
Pro-inflammatory cytokines cause pancreatic beta cell failure during the development of type 2 diabetes. This beta cell failure associates with mitochondrial dysfunction, but the precise effects of cytokines on mitochondrial respiration remain unclear ...
Affourtit, C, Barlow, J, Solomon, TPJ
core +3 more sources
Millimolar concentrations of free magnesium enhance exocytosis from permeabilized rat pheochromocytoma (PC 12) cells [PDF]
The role of Mg2+ during the final steps of exocytosis was investigated using rat pheochromocytoma cells (PC12) permeabilized with bacterial pore forming toxins.
Ahnert-Hilger +17 more
core +1 more source
Insulinoma Associated with MEN1 Syndrome: A Case of Persistent Hypoglycemia in a School-aged Child
Insulinoma is a rare cause of non-ketotic hypoglycemia, both in adults and in children. Pediatric patients account for approximately 5% of all cases, mostly due to isolated benign lesions, but insulinoma may also be part of a multiple endocrine neoplasia
Rodrigo Lemus-Zepeda +4 more
doaj +1 more source
Human insulinoma: Clinical, cellular, and molecular aspects [PDF]
Insulinoma is the most frequently encountered functioning endocrine pancreatic tumor in humans. In this overview we summarize morphological and clinical features of insulinomas, report about the proinsulin-insulin conversion in normal and neoplastic B ...
Heitz, Philipp +2 more
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