Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
The effect of food provisioning on the nutrient intake of wild and captive primates : implications for the conservation management of wild and captive populations : a thesis presented in partial fulfilment of the requirements for the degree of Doctorate of Philosophy in Ecology, Massey University, Albany, New Zealand [PDF]
, 2017 Many non-human primate populations worldwide are threatened with extinction. Various measures are taken to save these species. Amongst these efforts are habitat protection, restoration, and public education, including wildlife tourism.
Kreigenhofer, Brigitte Monique
core
Hypothalamic eIF2α Signaling Regulates Food Intake [PDF]
, 2014 Anne‐Catherine Maurin +15 more
openalex +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Intakes, adequacy, food sources and biomarker status of iron, folate, and vitamin B₁₂ in Māori and non-Māori octogenarians : life and living in advanced age : a cohort study in New Zealand (LiLACS NZ) : a thesis presented in partial fulfilment of the requirements for the degree of Masters of Science in Nutrition and Dietetics, Massey University, Albany, New Zealand [PDF]
, 2017 Background: Iron, folate and vitamin B12 are the three key nutrients associated with the development of anaemia and have also been associated with the dietary patterns linked to higher malnutrition risk in older adults.
Pillay, Danika
core
Increased Intake of Selected Vegetables, Herbs and Fruit may Reduce Bone Turnover in Post-Menopausal Women [PDF]
, 2015 Caroline Gunn +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Does socio-economic status moderate the associations between psychosocial predictors and fruit intake in schoolchildren? The Pro Children study [PDF]
, 2009 Camilla Sandvik +4 more
openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source