Results 101 to 110 of about 1,530,697 (251)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

INTAKE OF TROPICAL TANNINIFEROUS PLANTS BY GOATS AND SHEEP WHEN OFFERED AS A SOLE FEED

Tropical and Subtropical Agroecosystems, 2009
The intake of tropical tanniniferous plants (TTP) (Lysiloma latisiliquum, Piscidia piscipula and Acacia pennatula) when offered as a single feed to small ruminants could help to design a supplementation strategy looking for an anthelmintic effect.
Miguel A. Alonso-Díaz, Juan Felipe de Jesús Torres-Acosta, Carlos A. Sandoval-Castro, Hilda Lorena Canul-Ku, Herve Hoste   +4 more
doaj  

Impact of nutrition mentoring by dietetic students on knowledge, dietary intake, and nutritional status in pregnant women with chronic energy deficiency in South Sulawesi

Healthcare in Low-resource Settings
Chronic Energy Deficiency (CED) in pregnant women raises the risk of premature birth and low birth weight (LBW). This study evaluates the effectiveness of nutrition mentoring by dietetic students on the knowledge, intake, and nutritional status of ...
Nadimin Nadimin, Hijrah Asikin
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

DETERMINAÇÃO DA FASE LACTENTE-RUMINANTE DE CORDEIROS PELA TÉCNICA DO δ13C

Ciência Animal Brasileira, 2010
This study was conducted at University of Marília, SãoPaulo State, Brazil, aiming to determine the phase of intake transitionbetween exclusively liquid diet (milk) and diet based onmilk, grass and/or ration by lambs by δ13C technique.
Janaina Januário da Silva, Ciniro Costa, Carlos Ducatti, Alda Lúcia Gomes Monteiro, Clédson Augusto Garcia   +4 more
doaj  

Horário alternativo de ordenha e o comportamento ingestivo de vacas mestiças leiteiras em sistema de produção a pasto=Alternative milking time and feeding behavior of crossbred dairy cows in grazing production systems [PDF]

Acta Scientiarum: Animal Sciences, 2012
Objetivou-se avaliar a influência do horário de ordenha no comportamento ingestivo de vacas mestiças leiteiras no sistema de produção com o bezerro em pé.
Aline Kelly de Araújo Costa, Maurício Passos Garcia, Tiago Oliveira Brandão, Larissa Pires Barbosa, Jair de Araújo Marques, Lucas Mercês e Mercês   +5 more
doaj  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Associação da palma forrageira com diferentes tipos de volumosos em dietas para vacas em lactação: comportamento ingestivo e parâmetros fisiológicos = Association of the forage cactus with different types of forage in diets for lactating cows: ingestive behaviour and physiologic parameters

Acta Scientiarum: Animal Sciences, 2007
O experimento foi realizado de janeiro a abril de 2005, objetivando avaliar o comportamento ingestivo e os parâmetros fisiológicos de vacas da raça Holandesa em lactação, alimentadas com concentrado e palma forrageira associada a diferentes volumosos ...
Alenice Ozino Ramos, Antonia Sherlânea Chaves Veras, Marcelo de Andrade Ferreira, Marcilio de Azevedo, Renata Rodrigues da Silva, Anna Cristine Alencar Fotius   +5 more
doaj  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source