Results 111 to 120 of about 8,614,380 (320)

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

open access: yesAdvanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li   +23 more
wiley   +1 more source

Oscillatory and asymptotic properties of fractional delay differential equations

open access: yesElectronic Journal of Differential Equations, 2019
This article discusses the oscillatory and asymptotic properties of a test delay differential system involving a non-integer derivative order. We formulate corresponding criteria via explicit necessary and sufficient conditions that enable direct ...
Jan Cermak, Tomas Kisela
doaj  

Restrict-and-relax search for 0-1 mixed-integer programs

open access: yesEURO Journal on Computational Optimization, 2013
A highly desirable characteristic of methods for solving 0-1 mixed-integer programs is that they should be capable of producing high-quality solutions quickly.
Menal Guzelsoy   +2 more
doaj   +1 more source

Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation‐Informed Protein Language Model

open access: yesAdvanced Science, EarlyView.
A TP53‐specific predictor, CaVepP53, is developed by fine‐tuning ESMC on experimentally validated variants, quantifying pathogenicity via Euclidean distances. It outperforms general‐purpose models and extends to five cancer genes, enabling interpretable variant classification for precision medicine.
Huiying Chen   +15 more
wiley   +1 more source

Concerning the Solutions of Some Lebesgue-Ramanujan-Nagell Equations

open access: yesCommunications in Advanced Mathematical Sciences
In this paper, we provide a complete classification of the integer solutions to the Diophantine equation $x^2 + 3^a 19^b 73^c = \lambda y^n,$ where \( \lambda = 2^{\delta} \), \( x, y \geq 1 \), \( a, b, c, \delta \geq 0 \), \( n \geq 3 \), \( \gcd(x, y)
Mustafa Aydın, Murat Alan
doaj   +1 more source

Integer spin particles necessarily produce half-integer angular momentum in a simple complex and periodic Hamiltonian

open access: yes, 2006
Exact wave functions are is derived from an azimuthally periodic a self-consistent quantum Hamiltonian in 2+1 dimensions using both the Klein-Gordon and the Schroedinger equations. It isWe shown that, curiously, for both relativistic and non-relativistic
Shinbrot, Troy
core  

On the Number of Nonnegative Solutions to the Inequality a1 +....ar < n [PDF]

open access: yes, 2010
In this paper, we present a simple and fast method for counting the number of nonnegative integer solutions to the equality a1x1+a2x2+: : :+arxr = n where a1; a2; :::; ar and n are positive integers.
Farzaneh , A.   +3 more
core  

A Perspective on Interactive Theorem Provers in Physics

open access: yesAdvanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Photon‐Sphere Modes in Curved Optical Microcavities: A Black‐Hole Analogue Laser

open access: yesAdvanced Science, EarlyView.
An optical analogue of a Schwarzschild black hole is realized using curved microcavities that preserve light‐like geodesics. A new family of laser modes confined around the photon sphere is identified alongside conventional whispering‐gallery modes. Analytical theory, numerical simulations, and experiments reveal curvature‐induced confinement, enabling
Chenni Xu   +9 more
wiley   +1 more source

On $X$-coordinates of Pell equations which are repdigits

open access: yes, 2017
Let $b\ge 2$ be a given integer. In this paper, we show that there only finitely many positive integers $d$ which are not squares, such that the Pell equation $X^2-dY^2=1$ has two positive integer solutions $(X,Y)$ with the property that their $X ...
Faye, Bernadette, Luca, Florian
core  

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