Results 41 to 50 of about 32,689 (256)

Gray matter is targeted in first-attack multiple sclerosis. [PDF]

open access: yesPLoS ONE, 2013
The cause of multiple sclerosis (MS), its driving pathogenesis at the earliest stages, and what factors allow the first clinical attack to manifest remain unknown. Some imaging studies suggest gray rather than white matter may be involved early, and some
Steven E Schutzer   +11 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Transferable Adversarial Attack based on Integrated Gradients

open access: yesCoRR, 2022
The vulnerability of deep neural networks to adversarial examples has drawn tremendous attention from the community. Three approaches, optimizing standard objective functions, exploiting attention maps, and smoothing decision surfaces, are commonly used to craft adversarial examples.
Yi Huang 0013, Adams Wai-Kin Kong
openaire   +3 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Boosting Face Presentation Attack Detection in Multi-Spectral Videos Through Score Fusion of Wavelet Partition Images

open access: yesFrontiers in Big Data, 2022
Presentation attack detection (PAD) algorithms have become an integral requirement for the secure usage of face recognition systems. As face recognition algorithms and applications increase from constrained to unconstrained environments and in ...
Akshay Agarwal   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Improved Security Evaluation of SPN Block Ciphers and its Applications in the Single-key Attack on SKINNY

open access: yesIACR Transactions on Symmetric Cryptology, 2020
In this paper, a new method for evaluating the integral property, truncated and impossible differentials for substitution-permutation network (SPN) block ciphers is proposed. The main assumption is an explicit description/expression of the internal state
Wenying Zhang   +3 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Zero correlation-integral attack of MIBS block cipher

open access: yesTongxin xuebao, 2016
MIBS is a lightweight block cipher for extremely constrained environments such as RFID tags and sensor networks. The MIBS algorithm's ability to resist zero correlation-integral analysis was evaluated. An 8-round zero corre-lation linear distinguisher of
Qing-cong LIU   +3 more
doaj   +2 more sources

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