Results 51 to 60 of about 32,689 (256)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Bit-Based Evaluation of Lightweight Block Ciphers SLIM, LBC-IoT, and SLA by Mixed Integer Linear Programming

IET Information Security
Many lightweight block ciphers have been proposed for IoT devices that have limited resources. SLIM, LBC-IoT, and SLA are lightweight block ciphers developed for IoT systems.
Nobuyuki Sugio
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Improved integral cryptanalysis of block cipher Zodiac

Cybersecurity
Integral cryptanalysis is a pivotal technique in symmetric-key cryptography. This paper enhances the integral key-recovery analysis of the Feistel-based cipher Zodiac by introducing a systematic framework for identifying optimal key recovery attack paths.
Yi Guo, Danping Shi, Lei Hu, Xu Guo, Zhiru Chen   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Novel method of constructing the zero-sum distinguishers

Tongxin xuebao, 2012
A novel method of constructing the zero-sum distinguishers for AES-like permutations was proposed by considering the diffusion properties of these permutations,which have the similar construction.The method combined the higher-order integral attack and ...
Le DONG, Wen-ling WU, Shuang WU, Jian ZHOU   +3 more
doaj   +2 more sources

Multiset-Algebraic Cryptanalysis of Reduced Kuznyechik, Khazad, and secret SPNs

IACR Transactions on Symmetric Cryptology, 2017
We devise the first closed formula for the number of rounds of a blockcipher with secret components so that these components can be revealed using multiset, algebraic-degree, or division-integral properties, which in this case are equivalent.
Alex Biryukov, Dmitry Khovratovich, Léo Perrin   +2 more
doaj   +1 more source