Results 61 to 70 of about 33,695 (292)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Zero correlation-integral attack of MIBS block cipher

open access: yesTongxin xuebao, 2016
MIBS is a lightweight block cipher for extremely constrained environments such as RFID tags and sensor networks. The MIBS algorithm's ability to resist zero correlation-integral analysis was evaluated. An 8-round zero corre-lation linear distinguisher of
Qing-cong LIU   +3 more
doaj   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Bit-Based Evaluation of Lightweight Block Ciphers SLIM, LBC-IoT, and SLA by Mixed Integer Linear Programming

open access: yesIET Information Security
Many lightweight block ciphers have been proposed for IoT devices that have limited resources. SLIM, LBC-IoT, and SLA are lightweight block ciphers developed for IoT systems.
Nobuyuki Sugio
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Improved integral cryptanalysis of block cipher Zodiac

open access: yesCybersecurity
Integral cryptanalysis is a pivotal technique in symmetric-key cryptography. This paper enhances the integral key-recovery analysis of the Feistel-based cipher Zodiac by introducing a systematic framework for identifying optimal key recovery attack paths.
Yi Guo   +4 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Investigation of crack propagation in X38CrMoV5 (AISI H11) tool steel at elevated temperatures [PDF]

open access: yes, 2010
A method is developed to evaluate the surface fatigue damage of hot forming tools (forging, HPDC) that undergo thermo mechanical loading and environmental attack.
Rezaï-Aria, Farhad   +2 more
core   +1 more source

Improved integral attacks without full codebook

open access: yesIET Information Security, 2018
The integral attack, exploits the balanced property of the output in the distinguisher. Usually, adversaries append some rounds after the distinguisher, guess the corresponding key bits and check whether the target bits are balanced. Few works add rounds before the distinguisher to make the key recovery attack. In the first full‐round attack on MISTY1,
Zhihui Chu   +6 more
openaire   +1 more source

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