Results 81 to 90 of about 675,504 (282)

Discrete mathematical model of the scattering process of E-polarized wave on a periodic impedance grating

Visnik Harkivsʹkogo Nacionalʹnogo Universitetu im. V.N. Karazina. Cepiâ Matematika, Prikladna Matematika i Mehanika, 2019
The method of numerical modeling of wave scattering by periodic impedance grating is considered. In the case of a harmonic dependence of the field on time and the uniformity of the structure along a certain axis, the three-dimensional problem reduces to ...
Vladimir D. Dushkin, Stanislav Zhuchenko, Oleksii V. Kostenko   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

INTEGRAL TRANSFORMATION FOR THE THIRD BOUNDARY-VALUE PROBLEM OF NON-STATIONARY HEAT CONDUCTIVITY WITH A CONTINUOUS SPECTRUM OF EIGENVALUES

Тонкие химические технологии, 2017
The mathematical theory of constructing an integral transformation and the inversion formula for it for the third boundary value problem in a domain with a continuous spectrum of eigenvalues are developed.
E. M. Kartashov
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Control Problem for a Heat Conduction Equation with Neumann Boundary Condition

Vestnik KRAUNC: Fiziko-Matematičeskie Nauki
Previously, boundary control problems for a heat conduction equation with Dirichlet boundary condition were studied in a bounded domain. In this paper, we consider the boundary control problem for the heat conduction equation with Neumann boundary ...
Dekhkonov, F.N.
doaj   +1 more source

Boundary value problem with integral condition for a Blasius type equation

Nonlinear Analysis, 2016
The steady motion in the boundary layer along a thin flat plate, which is immersed at zero incidence in a uniform stream with constant velocity, can be described in terms of the solution of the differential equation x'''= -xx'', which satisfies the ...
Sergey Smirnov
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Distribution of the critical and other points in boundary problems with nonlocal boundary condition

Lietuvos Matematikos Rinkinys, 2007
In this paper the Sturm–Liouville problem with one classical and other nonlocal two-point or integral boundary condition is investigated. There are critical points of the characteristic function analysed.
Sigita Pečiulytė, Artūras Štikonas
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source