Results 101 to 110 of about 783,161 (291)
Multi-Term Fractional Differential Equations with Generalized Integral Boundary Conditions
Fractal and Fractional, 2019 We discuss the existence of solutions for a Caputo type multi-term nonlinear fractional differential equation supplemented with generalized integral boundary conditions.
Bashir Ahmad +3 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Advances in Difference Equations, 2011 This paper studies a boundary value problem of nonlinear fractional differential equations of order with three-point integral boundary conditions. Some new existence and uniqueness results are obtained by using standard fixed point theorems and Leray ...
Ntouyas SotirisK +2 more
doaj
Solvability of integral boundary value problems at resonance in Rn $R^{n}$
Journal of Inequalities and Applications, 2019 Under a resonance condition involving integral boundary value problems for a second-order nonlinear differential equation in Rn $\mathbb{R}^{n}$, we show its solvability by using the coincidence degree theory of Mawhin and the theory of matrix ...
Shiying Song, Shuman Meng, Yujun Cui
doaj +1 more source
Discrete-Time Path Distributions on Hilbert Space [PDF]
, 2012 We construct a path distribution representing the kinetic part of the Feynman path integral at discrete times similar to that defined by Thomas [1], but on a Hilbert space of paths rather than a nuclear sequence space. We also consider different boundary
Beau, Mathieu, Dorlas, T. C.
core +4 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Investigation of the spectrum for the Sturm-Liouville problem with one integral boundary condition
Nonlinear Analysis, 2010 In this paper, the Sturm–Liouville problem with one classical first type boundary condition and other nonlocal integral boundary conditions of two cases is investigated.
A. Skučaitė +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Multi-term fractional-order boundary-value problems with nonlocal integral boundary conditions
Electronic Journal of Differential Equations, 2018 In this article, we introduce a class of multi-term fractional-order boundary-value problems involving nonlocal integral boundary conditions. Existence results for the given problem are obtained by means of standard tools of fixed point theory.
Ahmed Alsaedi +4 more
doaj
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source